Cell atlas - ZNF300 - The Human Protein Atlas

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ZNF300

TISSUE

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CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nucleoli
	Nucleoplasm

Human cell
	Nucleoli
	Nucleoplasm

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GENERAL INFORMATION
Gene name	ZNF300
Gene description	Zinc finger protein 300
Protein class	Cancer-related genes Plasma proteins Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the nucleoli & nucleoplasm.
RNA cell category	Mixed
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoplasm (supported), Nucleoli (supported)

DATA RELIABILITY
Reliability score	Supported based on 1 antibody. HPA028975
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Mixed Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the nucleoli & nucleoplasm.

Main location

Nucleoplasm (supported), Nucleoli (supported)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA028975	HeLa	Nucleoplasm
	HPA028975	HeLa	Nucleoli
	HPA028975	SH-SY5Y	Nucleus
	HPA028975	U-2 OS	Nucleoplasm
	HPA028975	U-2 OS	Nucleoli

GENE INFORMATION
Gene name	ZNF300
Synonyms
Description	Zinc finger protein 300 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is a C2H2-type zinc finger DNA binding protein and likely transcriptional regulator. The function of this protein is not yet known. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010]
Chromosome	5
Cytoband	q33.1
Chromosome location (bp)	150894392 - 150904983
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000145908 (version 83.38)
Entrez gene	91975
UniProt	Q96RE9 (UniProt - Evidence at protein level)
neXtProt	NX_Q96RE9
Antibodypedia	ZNF300 antibodies

PROTEIN BROWSER

ZNF300-001	ZNF300-002	ZNF300-201	ZNF300-202	ZNF300-203

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ZNF300-001 ENSP00000377773 ENST00000394226	A0A0A0MS50 [Direct mapping] Zinc finger protein 300 Show all	Predicted intracellular proteins Cancer-related genes Mutational cancer driver genes Show all	GO:0003676 [nucleic acid binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005622 [intracellular] GO:0006355 [regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	604 aa 68.7 kDa	No	0
ZNF300-002 ENSP00000414195 ENST00000427179	F8WE31 [Direct mapping] Zinc finger protein 300 Show all	Predicted intracellular proteins Cancer-related genes Mutational cancer driver genes Show all	GO:0003676 [nucleic acid binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005622 [intracellular] GO:0006355 [regulation of transcription, DNA-templated] Show all	90 aa 10.5 kDa	No	0
ZNF300-201 ENSP00000274599 ENST00000274599	Q96RE9 [Direct mapping] Zinc finger protein 300 Show all	Predicted intracellular proteins Plasma proteins Transcription factors Zinc-coordinating DNA-binding domains Cancer-related genes Mutational cancer driver genes Protein evidence (Kim et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0003677 [DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	604 aa 68.7 kDa	No	0
ZNF300-202 ENSP00000392593 ENST00000418587	Q96RE9 [Direct mapping] Zinc finger protein 300 Show all	Predicted intracellular proteins Plasma proteins Transcription factors Zinc-coordinating DNA-binding domains Cancer-related genes Mutational cancer driver genes Protein evidence (Kim et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0003677 [DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	568 aa 64.5 kDa	No	0
ZNF300-203 ENSP00000397178 ENST00000446148	Q96RE9 [Direct mapping] Zinc finger protein 300 Show all	Predicted intracellular proteins Plasma proteins Transcription factors Zinc-coordinating DNA-binding domains Cancer-related genes Mutational cancer driver genes Protein evidence (Kim et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0003677 [DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	620 aa 70.4 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.