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HIST1H2BA

CANCER ATLAS

Gene description

 Histone cluster 1, H2ba

Protein class

 Predicted intracellular proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA042205
HPA043013
CAB011603

GENE INFORMATION

Gene name

 HIST1H2BA (HGNC Symbol)

Synonyms

 bA317E16.3, H2BFU, STBP, TSH2B

Description

 Histone cluster 1, H2ba (HGNC Symbol)

Entrez gene summary

 Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a testis/sperm-specific member of the histone H2B family. Transcripts from this gene contain a palindromic termination element. [provided by RefSeq, Aug 2015]

Chromosome

 6

Cytoband

 p22.2

Chromosome location (bp)

 25726909 - 25727292

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000146047 (version 83.38)

Entrez gene

 255626

UniProt

 Q96A08 (UniProt - Evidence at protein level)

neXtProt

 NX_Q96A08

Antibodypedia

 HIST1H2BA antibodies

PROTEIN BROWSER
HIST1H2BA-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
HIST1H2BA-001
ENSP00000274764
ENST00000274764
Q96A08 [Direct mapping]
Histone H2B type 1-A
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000784 [nuclear chromosome, telomeric region]
GO:0000786 [nucleosome]
GO:0000788 [nuclear nucleosome]
GO:0003674 [molecular_function]
GO:0003677 [DNA binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0006325 [chromatin organization]
GO:0006334 [nucleosome assembly]
GO:0006337 [nucleosome disassembly]
GO:0006954 [inflammatory response]
GO:0019897 [extrinsic component of plasma membrane]
GO:0031639 [plasminogen activation]
GO:0035093 [spermatogenesis, exchange of chromosomal proteins]
GO:0046982 [protein heterodimerization activity]
GO:0051099 [positive regulation of binding]
GO:0071674 [mononuclear cell migration]
Show all
 127 aa
14.2 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.