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Most cancer tissues displayed moderate to strong cytoplasmic positivity with a granular pattern. Lymphomas, melanomas and renal cancers and several cases of gliomas and hepatocellular carcinomas were weakly stained or negative.
GENE INFORMATION
Gene name
TRIM41 (HGNC Symbol)
Synonyms
MGC1127, RINCK
Description
Tripartite motif containing 41 (HGNC Symbol)
Entrez gene summary
This gene encodes a member of the tripartite motif (TRIM) family. The TRIM family is characterized by a signature motif composed of a RING finger, one or more B-box domains, and a coiled-coil region. This encoded protein may play a role in protein kinase C signaling. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]