Expression of HIGD2A in cancer - Summary

CANCER ATLAS

Gene description

HIG1 hypoxia inducible domain family, member 2A

Protein class

Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA042715

GENE INFORMATION
Gene name	HIGD2A (HGNC Symbol)
Synonyms	MGC2198
Description	HIG1 hypoxia inducible domain family, member 2A (HGNC Symbol)
Entrez gene summary
Chromosome	5
Cytoband	q35.2
Chromosome location (bp)	176388747 - 176389771
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000146066 (version 83.38)
Entrez gene	192286
UniProt	Q9BW72 (UniProt - Evidence at protein level)
neXtProt	NX_Q9BW72
Antibodypedia	HIGD2A antibodies

PROTEIN BROWSER

HIGD2A-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
HIGD2A-001 ENSP00000274787 ENST00000274787	Q9BW72 [Direct mapping] HIG1 domain family member 2A, mitochondrial A0A024R7Q3 [Target identity:100%; Query identity:100%] HIG1 domain family, member 2A, isoform CRA_a Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005743 [mitochondrial inner membrane] GO:0016021 [integral component of membrane] GO:0043066 [negative regulation of apoptotic process] GO:0055114 [oxidation-reduction process] GO:0070469 [respiratory chain] Show all	106 aa 11.5 kDa	No	2