Expression of TRIM50 in cancer - Summary - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

TRIM50

TISSUE

CELL

CANCER

CANCER ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

CANCER ATLAS

Gene description

Tripartite motif containing 50

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA019862

Tissue	Cancer staining
Breast cancer
Carcinoid
Cervical cancer
Colorectal cancer
Endometrial cancer
Glioma
Head and neck cancer
Liver cancer
Lung cancer
Lymphoma

Tissue	Cancer staining
Melanoma
Ovarian cancer
Pancreatic cancer
Prostate cancer
Renal cancer
Skin cancer
Stomach cancer
Testis cancer
Thyroid cancer
Urothelial cancer

Staining summary	Weak to moderate cytoplasmic staining was observed in most malignancies. Several prostate, breast ad urothelial cancers were strongly stained while several renal cancers were negative.

GENE INFORMATION
Gene name	TRIM50 (HGNC Symbol)
Synonyms	FLJ32804, TRIM50A
Description	Tripartite motif containing 50 (HGNC Symbol)
Entrez gene summary
Chromosome	7
Cytoband	q11.23
Chromosome location (bp)	73312539 - 73328082
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000146755 (version 83.38)
Entrez gene	135892
UniProt	Q86XT4 (UniProt - Evidence at protein level)
neXtProt	NX_Q86XT4
Antibodypedia	TRIM50 antibodies

PROTEIN BROWSER

TRIM50-001	TRIM50-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TRIM50-001 ENSP00000327994 ENST00000333149	Q86XT4 [Direct mapping] E3 ubiquitin-protein ligase TRIM50 Q2M204 [Target identity:100%; Query identity:100%] HCG1642804, isoform CRA_b; Tripartite motif protein 50A; cDNA FLJ77582, highly similar to Homo sapiens tripartite motif-containing 50A (TRIM50A), mRNA Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0005737 [cytoplasm] GO:0008152 [metabolic process] GO:0008270 [zinc ion binding] GO:0016235 [aggresome] GO:0016874 [ligase activity] GO:0070201 [regulation of establishment of protein localization] Show all	487 aa 54.7 kDa	No	0
TRIM50-002 ENSP00000413875 ENST00000453152	Q86XT4 [Direct mapping] E3 ubiquitin-protein ligase TRIM50 Q2M204 [Target identity:100%; Query identity:100%] HCG1642804, isoform CRA_b; Tripartite motif protein 50A; cDNA FLJ77582, highly similar to Homo sapiens tripartite motif-containing 50A (TRIM50A), mRNA Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0005737 [cytoplasm] GO:0008152 [metabolic process] GO:0008270 [zinc ion binding] GO:0016874 [ligase activity] Show all	487 aa 54.7 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.