Cell atlas - KRBOX4 - The Human Protein Atlas

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KRBOX4

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nucleoplasm

Human cell
	Nucleoplasm

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GENERAL INFORMATION
Gene name	KRBOX4
Gene description	KRAB box domain containing 4
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	6
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the nucleoplasm. Caution: Based on antibodies targeting proteins from multiple genes.
RNA cell category	Mixed
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoplasm (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA065295
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Mixed Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the nucleoplasm. Caution: Based on antibodies targeting proteins from multiple genes.

Main location

Nucleoplasm (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA065295	RH-30	Nucleoplasm
	HPA065295	SK-MEL-30	Nucleoplasm
	HPA065295	U-2 OS	Nucleoplasm

GENE INFORMATION
Gene name	KRBOX4 (HGNC Symbol)
Synonyms	FLJ20344, ZNF673
Description	KRAB box domain containing 4 (HGNC Symbol)
Entrez gene summary	This encodes a zinc finger protein with an N-terminal KRAB (Kruppel-associated) domain found in transcriptional repressors. This gene is located in a region of the X chromosome thought to be involved in nonsyndromic X-linked mental retardation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
Chromosome	X
Cytoband	p11.3
Chromosome location (bp)	46446857 - 46497422
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000147121 (version 83.38)
Entrez gene	55634
UniProt	Q5JUW0 (UniProt - Evidence at transcript level)
neXtProt	NX_Q5JUW0
Antibodypedia	KRBOX4 antibodies

PROTEIN BROWSER

KRBOX4-001	KRBOX4-002	KRBOX4-003	KRBOX4-004	KRBOX4-005	KRBOX4-007

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
KRBOX4-001 ENSP00000418146 ENST00000478600	C9J950 [Direct mapping] KRAB domain-containing protein 4 Show all	Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0005622 [intracellular] GO:0006355 [regulation of transcription, DNA-templated] Show all	93 aa 10.5 kDa	No	0
KRBOX4-002 ENSP00000345797 ENST00000344302	Q5JUW0 [Direct mapping] KRAB domain-containing protein 4 Show all	Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0005622 [intracellular] GO:0006355 [regulation of transcription, DNA-templated] Show all	171 aa 20.1 kDa	No	0
KRBOX4-003 ENSP00000367152 ENST00000377919	Q5JUW0 [Direct mapping] KRAB domain-containing protein 4 Show all	Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0005622 [intracellular] GO:0006355 [regulation of transcription, DNA-templated] Show all	98 aa 11.1 kDa	No	0
KRBOX4-004 ENSP00000418076 ENST00000487081	Q5JUW0 [Direct mapping] KRAB domain-containing protein 4 Show all	Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0005622 [intracellular] GO:0006355 [regulation of transcription, DNA-templated] Show all	98 aa 11.1 kDa	No	0
KRBOX4-005 ENSP00000298190 ENST00000298190	Q5JUW0 [Direct mapping] KRAB domain-containing protein 4 Show all	Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0005622 [intracellular] GO:0006355 [regulation of transcription, DNA-templated] Show all	166 aa 19.5 kDa	No	0
KRBOX4-007 ENSP00000418205 ENST00000476762	C9J804 [Direct mapping] KRAB domain-containing protein 4 Show all	Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0005622 [intracellular] GO:0006355 [regulation of transcription, DNA-templated] Show all	131 aa 14.4 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.