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Weak to moderate nuclear positivity was observed in most cancer tissues. Several basal cell carcinomas were strongly stained. Several liver and prostate cancers were negative.
GENE INFORMATION
Gene name
ZNF41 (HGNC Symbol)
Synonyms
MGC8941, MRX89
Description
Zinc finger protein 41 (HGNC Symbol)
Entrez gene summary
This gene product is a likely zinc finger family transcription factor. It contains KRAB-A and KRAB-B domains that act as transcriptional repressors in related proteins, and multiple zinc finger DNA binding motifs and finger linking regions characteristic of the Kruppel family. This gene is part of a gene cluster on chromosome Xp11.23. Several alternatively spliced transcript variants have been described, however, the full-length nature of only some of them is known. [provided by RefSeq, Jul 2008]