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CETN2

GENERAL INFORMATION

Gene name

 CETN2

Gene description

 Centrin, EF-hand protein, 2

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression in several tissues, most abundant in testis.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data. Caution, targets protein from more than one gene. Pending external verification.

Reliability score

 Uncertain based on 1 antibody.
HPA028956
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 CETN2 (HGNC Symbol)

Synonyms

 CALT, CEN2

Description

 Centrin, EF-hand protein, 2 (HGNC Symbol)

Entrez gene summary

 Caltractin belongs to a family of calcium-binding proteins and is a structural component of the centrosome. The high level of conservation from algae to humans and its association with the centrosome suggested that caltractin plays a fundamental role in the structure and function of the microtubule-organizing center, possibly required for the proper duplication and segregation of the centrosome. [provided by RefSeq, Jul 2008]

Chromosome

 X

Cytoband

 q28

Chromosome location (bp)

 152826973 - 152830777

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000147400 (version 83.38)

Entrez gene

 1069

UniProt

 P41208 (UniProt - Evidence at protein level)

neXtProt

 NX_P41208

Antibodypedia

 CETN2 antibodies

PROTEIN BROWSER
CETN2-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
CETN2-001
ENSP00000359300
ENST00000370277
P41208 [Direct mapping]
Centrin-2
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0000086 [G2/M transition of mitotic cell cycle]
GO:0000278 [mitotic cell cycle]
GO:0000715 [nucleotide-excision repair, DNA damage recognition]
GO:0005509 [calcium ion binding]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005654 [nucleoplasm]
GO:0005813 [centrosome]
GO:0005814 [centriole]
GO:0005829 [cytosol]
GO:0005929 [cilium]
GO:0006281 [DNA repair]
GO:0006289 [nucleotide-excision repair]
GO:0006996 [organelle organization]
GO:0007067 [mitotic nuclear division]
GO:0007099 [centriole replication]
GO:0007283 [spermatogenesis]
GO:0008017 [microtubule binding]
GO:0016925 [protein sumoylation]
GO:0031683 [G-protein beta/gamma-subunit complex binding]
GO:0032391 [photoreceptor connecting cilium]
GO:0032465 [regulation of cytokinesis]
GO:0032795 [heterotrimeric G-protein binding]
GO:0036064 [ciliary basal body]
GO:0043687 [post-translational protein modification]
GO:0044267 [cellular protein metabolic process]
GO:0051301 [cell division]
GO:0070911 [global genome nucleotide-excision repair]
GO:0071942 [XPC complex]
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 172 aa
19.7 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.