Expression of EIF3H in cancer - Summary

CANCER ATLAS

Gene description

Eukaryotic translation initiation factor 3, subunit H

Protein class

Cancer-related genes, Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA023117	HPA023553

GENE INFORMATION
Gene name	EIF3H (HGNC Symbol)
Synonyms	eIF3-gamma, eIF3-p40, eIF3h, EIF3S3
Description	Eukaryotic translation initiation factor 3, subunit H (HGNC Symbol)
Entrez gene summary
Chromosome	8
Cytoband
Chromosome location (bp)	116642130 - 116766925
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000147677 (version 83.38)
Entrez gene	8667
UniProt	O15372 (UniProt - Evidence at protein level)
neXtProt	NX_O15372
Antibodypedia	EIF3H antibodies

PROTEIN BROWSER

EIF3H-001	EIF3H-003	EIF3H-004	EIF3H-007	EIF3H-008	EIF3H-009	EIF3H-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
EIF3H-001 ENSP00000429931 ENST00000521861	O15372 [Direct mapping] Eukaryotic translation initiation factor 3 subunit H Q6IB98 [Target identity:100%; Query identity:100%] Eukaryotic translation initiation factor 3 subunit H Show all	Predicted intracellular proteins Cancer-related genes Candidate cancer biomarkers Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0001731 [formation of translation preinitiation complex] GO:0003743 [translation initiation factor activity] GO:0005515 [protein binding] GO:0005829 [cytosol] GO:0005852 [eukaryotic translation initiation factor 3 complex] GO:0006412 [translation] GO:0006413 [translational initiation] GO:0006446 [regulation of translational initiation] GO:0010467 [gene expression] GO:0016020 [membrane] GO:0016282 [eukaryotic 43S preinitiation complex] GO:0033290 [eukaryotic 48S preinitiation complex] GO:0044267 [cellular protein metabolic process] GO:0044822 [poly(A) RNA binding] GO:0070062 [extracellular exosome] GO:0071541 [eukaryotic translation initiation factor 3 complex, eIF3m] Show all	352 aa 39.9 kDa	No	0
EIF3H-003 ENSP00000276682 ENST00000276682	B3KS98 [Direct mapping] Eukaryotic translation initiation factor 3 subunit H Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0001731 [formation of translation preinitiation complex] GO:0003743 [translation initiation factor activity] GO:0005515 [protein binding] GO:0005852 [eukaryotic translation initiation factor 3 complex] GO:0016282 [eukaryotic 43S preinitiation complex] GO:0033290 [eukaryotic 48S preinitiation complex] Show all	366 aa 41.6 kDa	No	0
EIF3H-004 ENSP00000427908 ENST00000520813	E5RFW7 [Direct mapping] Eukaryotic translation initiation factor 3 subunit H Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003743 [translation initiation factor activity] GO:0005515 [protein binding] GO:0005852 [eukaryotic translation initiation factor 3 complex] GO:0006413 [translational initiation] Show all	97 aa 10.1 kDa	No	0
EIF3H-007 ENSP00000428669 ENST00000518995	E5RGU4 [Direct mapping] Eukaryotic translation initiation factor 3 subunit H Show all	SCAMPI predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003743 [translation initiation factor activity] GO:0005515 [protein binding] GO:0005852 [eukaryotic translation initiation factor 3 complex] GO:0006413 [translational initiation] Show all	235 aa 26.2 kDa	No	0
EIF3H-008 ENSP00000428195 ENST00000518949	E5RJT0 [Direct mapping] Eukaryotic translation initiation factor 3 subunit H Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003743 [translation initiation factor activity] GO:0005515 [protein binding] GO:0005852 [eukaryotic translation initiation factor 3 complex] GO:0006413 [translational initiation] Show all	244 aa 28.4 kDa	No	0
EIF3H-009 ENSP00000428885 ENST00000522453	E5RFH0 [Direct mapping] Eukaryotic translation initiation factor 3 subunit H Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003743 [translation initiation factor activity] GO:0005515 [protein binding] GO:0005852 [eukaryotic translation initiation factor 3 complex] GO:0006413 [translational initiation] Show all	170 aa 18.7 kDa	No	0
EIF3H-201 ENSP00000482724 ENST00000611080	A0A087WZK9 [Direct mapping] Eukaryotic translation initiation factor 3 subunit H Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0001731 [formation of translation preinitiation complex] GO:0003743 [translation initiation factor activity] GO:0005515 [protein binding] GO:0005852 [eukaryotic translation initiation factor 3 complex] GO:0016282 [eukaryotic 43S preinitiation complex] GO:0033290 [eukaryotic 48S preinitiation complex] Show all	349 aa 39.6 kDa	No	0