Cell atlas - ZNF462 - The Human Protein Atlas

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ZNF462

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nucleoplasm

Human cell
	Nucleoplasm

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GENERAL INFORMATION
Gene name	ZNF462
Gene description	Zinc finger protein 462
Protein class	Plasma proteins Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the nucleoplasm.
RNA cell category	Mixed
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoplasm (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA022283
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Mixed Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the nucleoplasm.

Main location

Nucleoplasm (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA022283	A-431	Nucleoplasm
	HPA022283	U-2 OS	Nucleoplasm
	HPA022283	U-251 MG	Nucleoplasm

GENE INFORMATION
Gene name	ZNF462 (HGNC Symbol)
Synonyms	DKFZP762N2316, KIAA1803, Zfp462
Description	Zinc finger protein 462 (HGNC Symbol)
Entrez gene summary
Chromosome	9
Cytoband	q31.2
Chromosome location (bp)	106863097 - 107013634
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000148143 (version 83.38)
Entrez gene	58499
UniProt	Q96JM2 (UniProt - Evidence at protein level)
neXtProt	NX_Q96JM2
Antibodypedia	ZNF462 antibodies

PROTEIN BROWSER

ZNF462-001	ZNF462-002	ZNF462-003	ZNF462-009	ZNF462-010

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ZNF462-001 ENSP00000277225 ENST00000277225	Q96JM2 [Direct mapping] Zinc finger protein 462 Show all	Predicted intracellular proteins Plasma proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003677 [DNA binding] GO:0005634 [nucleus] GO:0006325 [chromatin organization] GO:0006351 [transcription, DNA-templated] GO:0043392 [negative regulation of DNA binding] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0046872 [metal ion binding] Show all	2506 aa 284.7 kDa	No	0
ZNF462-002 ENSP00000363818 ENST00000374686	H3BLX4 [Direct mapping] Zinc finger protein 462 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0046872 [metal ion binding] Show all	1449 aa 165.7 kDa	No	0
ZNF462-003 ENSP00000405837 ENST00000427098	H0Y6H9 [Direct mapping] Zinc finger protein 462 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		208 aa 23.2 kDa	No	0
ZNF462-009 ENSP00000397306 ENST00000441147	Q96JM2 [Direct mapping] Zinc finger protein 462 Show all	Predicted intracellular proteins Plasma proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Ezkurdia et al 2014) Show all	GO:0003677 [DNA binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	1412 aa 161.5 kDa	No	0
ZNF462-010 ENSP00000476222 ENST00000472574	U3KQU3 [Direct mapping] Zinc finger protein 462 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		110 aa 12 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.