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GTF3C5

GENERAL INFORMATION

Gene name

 GTF3C5

Gene description

 General transcription factor IIIC, polypeptide 5, 63kDa

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 7
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Nuclear expression in all tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. Presumed off target binding observed in the cytoplasm of smooth muscle cells and disregarded.

Reliability score

 Supported based on 1 antibody.
HPA067063
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Skin

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 GTF3C5 (HGNC Symbol)

Synonyms

 TFiiiC2-63, TFIIIC63, TFIIICepsilon

Description

 General transcription factor IIIC, polypeptide 5, 63kDa (HGNC Symbol)

Entrez gene summary

Chromosome

 9

Cytoband

 q34.13

Chromosome location (bp)

 133030675 - 133058503

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000148308 (version 83.38)

Entrez gene

 9328

UniProt

 Q9Y5Q8 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9Y5Q8

Antibodypedia

 GTF3C5 antibodies

PROTEIN BROWSER
GTF3C5-001
GTF3C5-003
GTF3C5-004
GTF3C5-005
GTF3C5-006
GTF3C5-007
GTF3C5-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
GTF3C5-001
ENSP00000397961
ENST00000435745
H0Y5D2 [Direct mapping]
General transcription factor 3C polypeptide 5
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 90 aa
9.4 kDa 		No 0
GTF3C5-003
ENSP00000361169
ENST00000372097
Q9Y5Q8 [Direct mapping]
General transcription factor 3C polypeptide 5
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000127 [transcription factor TFIIIC complex]
GO:0003677 [DNA binding]
GO:0005515 [protein binding]
GO:0005654 [nucleoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006383 [transcription from RNA polymerase III promoter]
GO:0010467 [gene expression]
GO:0042791 [5S class rRNA transcription from RNA polymerase III type 1 promoter]
GO:0042797 [tRNA transcription from RNA polymerase III promoter]
Show all
 519 aa
59.6 kDa 		No 0
GTF3C5-004
ENSP00000361180
ENST00000372108
Q9Y5Q8 [Direct mapping]
General transcription factor 3C polypeptide 5
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000127 [transcription factor TFIIIC complex]
GO:0003677 [DNA binding]
GO:0005515 [protein binding]
GO:0005654 [nucleoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006383 [transcription from RNA polymerase III promoter]
GO:0010467 [gene expression]
GO:0035914 [skeletal muscle cell differentiation]
GO:0042791 [5S class rRNA transcription from RNA polymerase III type 1 promoter]
GO:0042797 [tRNA transcription from RNA polymerase III promoter]
Show all
 526 aa
60.4 kDa 		No 0
GTF3C5-005
ENSP00000339530
ENST00000342018
Q5T7U1 [Direct mapping]
General transcription factor 3C polypeptide 5; General transcription factor IIIC, polypeptide 5, 63kDa, isoform CRA_c
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 457 aa
52.3 kDa 		No 0
GTF3C5-006
ENSP00000389498
ENST00000440319
Q5T7U4 [Direct mapping]
General transcription factor 3C polypeptide 5
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 244 aa
28.5 kDa 		No 0
GTF3C5-007
ENSP00000393207
ENST00000439697
Q5T7U0 [Direct mapping]
General transcription factor 3C polypeptide 5
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 224 aa
26.3 kDa 		No 0
GTF3C5-201
ENSP00000361171
ENST00000372099
H7BY84 [Direct mapping]
General transcription factor 3C polypeptide 5
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 345 aa
39.7 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.