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Most cancer tissues showed weak to moderate nuclear staining and additional cytoplasmic positivity in a few cases. Several renal cell carcinomas were negative.
GENE INFORMATION
Gene name
CIZ1 (HGNC Symbol)
Synonyms
LSFR1, ZNF356
Description
CDKN1A interacting zinc finger protein 1 (HGNC Symbol)
Entrez gene summary
The protein encoded by this gene is a zinc finger DNA binding protein that interacts with CIP1, part of a complex with cyclin E. The encoded protein may regulate the cellular localization of CIP1. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]