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Most of cancer tissues showed weak to moderate cytoplasmic immunoreactivity with a granular pattern. Thyroid cancers and a few cases of ovarian cancers were strongly stained. Most seminomas, hepatocellular carcinomas and renal cancers were negative.
Most cancer tissues showed weak to moderate cytoplasmic staining. Basal cell carcinomas of skin showed strong cytoplasmic and membranous staining. A few cases of gliomas and occasional pancreatic cancers were strongly stained. Many lymphomas, cervical, urothelial, stomach and liver cancers were negative.
GENE INFORMATION
Gene name
FAM188A (HGNC Symbol)
Synonyms
C10orf97, CARP, DERP5, FLJ13397, my042
Description
Family with sequence similarity 188, member A (HGNC Symbol)
Entrez gene summary
C10ORF97 is a member of the caspase-associated recruitment domain (CARD) family of proteins that play a role in apoptosis (Liu et al., 2002 [PubMed 12054670]).[supplied by OMIM, Mar 2008]
MEMSAT3 predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)