Expression of ADIRF in cancer - Summary

CANCER ATLAS

Gene description

Adipogenesis regulatory factor

Protein class

Plasma proteins, Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Urothelial cancer

STAINING SUMMARY

HPA026810

GENE INFORMATION
Gene name	ADIRF (HGNC Symbol)
Synonyms	AFRO, APM2, C10orf116
Description	Adipogenesis regulatory factor (HGNC Symbol)
Entrez gene summary	APM2 gene is exclusively expressed in adipose tissue. Its function is currently unknown. [provided by RefSeq, Jul 2008]
Chromosome	10
Cytoband	q23.2
Chromosome location (bp)	86968192 - 86983934
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000148671 (version 83.38)
Entrez gene	10974
UniProt	Q15847 (UniProt - Evidence at protein level)
neXtProt	NX_Q15847
Antibodypedia	ADIRF antibodies

PROTEIN BROWSER

ADIRF-001	ADIRF-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ADIRF-001 ENSP00000361083 ENST00000372013	Q15847 [Direct mapping] Adipogenesis regulatory factor Q5TBU5 [Target identity:100%; Query identity:100%] HCG1773630; cDNA, FLJ92308, Homo sapiens adipose specific 2 (APM2), mRNA Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0006351 [transcription, DNA-templated] GO:0030154 [cell differentiation] GO:0045600 [positive regulation of fat cell differentiation] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0070062 [extracellular exosome] GO:0071478 [cellular response to radiation] GO:0072719 [cellular response to cisplatin] GO:2001023 [regulation of response to drug] Show all	76 aa 7.9 kDa	No	0
ADIRF-002 ENSP00000394643 ENST00000416348	Q5TBU2 [Direct mapping] Adipogenesis regulatory factor Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		38 aa 4.1 kDa	No	0