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GLYAT

CANCER ATLAS

Gene description

 Glycine-N-acyltransferase

Protein class

 Enzymes, Predicted intracellular proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA040251
HPA044094

GENE INFORMATION

Gene name

 GLYAT (HGNC Symbol)

Synonyms

 ACGNAT, GAT

Description

 Glycine-N-acyltransferase (HGNC Symbol)

Entrez gene summary

 The glycine-N-acyltransferase protein conjugates glycine with acyl-CoA substrates in the mitochondria. The protein is thought to be important in the detoxification of endogenous and xenobiotic acyl-CoA's. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

 11

Cytoband

 q12.1

Chromosome location (bp)

 58640426 - 58731974

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000149124 (version 83.38)

Entrez gene

 10249

UniProt

 Q6IB77 (UniProt - Evidence at protein level)

neXtProt

 NX_Q6IB77

Antibodypedia

 GLYAT antibodies

PROTEIN BROWSER
GLYAT-001
GLYAT-002
GLYAT-004
GLYAT-005
GLYAT-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
GLYAT-001
ENSP00000278400
ENST00000278400
Q6IB77 [Direct mapping]
Glycine N-acyltransferase
Show all
Enzymes
   ENZYME proteins
   Transferases
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005739 [mitochondrion]
GO:0005759 [mitochondrial matrix]
GO:0006544 [glycine metabolic process]
GO:0006637 [acyl-CoA metabolic process]
GO:0006805 [xenobiotic metabolic process]
GO:0009636 [response to toxic substance]
GO:0016746 [transferase activity, transferring acyl groups]
GO:0032787 [monocarboxylic acid metabolic process]
GO:0044281 [small molecule metabolic process]
GO:0047961 [glycine N-acyltransferase activity]
GO:0047962 [glycine N-benzoyltransferase activity]
GO:0070062 [extracellular exosome]
Show all
 163 aa
18.5 kDa 		No 0
GLYAT-002
ENSP00000340200
ENST00000344743
Q6IB77 [Direct mapping]
Glycine N-acyltransferase
Show all
Enzymes
   ENZYME proteins
   Transferases
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005739 [mitochondrion]
GO:0005759 [mitochondrial matrix]
GO:0006544 [glycine metabolic process]
GO:0006637 [acyl-CoA metabolic process]
GO:0006805 [xenobiotic metabolic process]
GO:0009636 [response to toxic substance]
GO:0016746 [transferase activity, transferring acyl groups]
GO:0032787 [monocarboxylic acid metabolic process]
GO:0044281 [small molecule metabolic process]
GO:0047961 [glycine N-acyltransferase activity]
GO:0047962 [glycine N-benzoyltransferase activity]
GO:0070062 [extracellular exosome]
Show all
 296 aa
33.9 kDa 		No 0
GLYAT-004
ENSP00000431688
ENST00000529732
Q6IB77 [Direct mapping]
Glycine N-acyltransferase
Show all
Enzymes
   ENZYME proteins
   Transferases
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005739 [mitochondrion]
GO:0005759 [mitochondrial matrix]
GO:0006544 [glycine metabolic process]
GO:0006637 [acyl-CoA metabolic process]
GO:0006805 [xenobiotic metabolic process]
GO:0009636 [response to toxic substance]
GO:0016746 [transferase activity, transferring acyl groups]
GO:0032787 [monocarboxylic acid metabolic process]
GO:0044281 [small molecule metabolic process]
GO:0047961 [glycine N-acyltransferase activity]
GO:0047962 [glycine N-benzoyltransferase activity]
GO:0070062 [extracellular exosome]
Show all
 296 aa
33.9 kDa 		No 0
GLYAT-005
ENSP00000468512
ENST00000586098
K7ES21 [Direct mapping]
Glycine N-acyltransferase
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005739 [mitochondrion]
GO:0008152 [metabolic process]
GO:0047961 [glycine N-acyltransferase activity]
Show all
 71 aa
7.9 kDa 		No 0
GLYAT-201
ENSP00000484592
ENST00000611865
Q6IB77 [Direct mapping]
Glycine N-acyltransferase
Show all
Enzymes
   ENZYME proteins
   Transferases
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005739 [mitochondrion]
GO:0005759 [mitochondrial matrix]
GO:0006544 [glycine metabolic process]
GO:0006637 [acyl-CoA metabolic process]
GO:0006805 [xenobiotic metabolic process]
GO:0009636 [response to toxic substance]
GO:0016746 [transferase activity, transferring acyl groups]
GO:0032787 [monocarboxylic acid metabolic process]
GO:0044281 [small molecule metabolic process]
GO:0047961 [glycine N-acyltransferase activity]
GO:0047962 [glycine N-benzoyltransferase activity]
GO:0070062 [extracellular exosome]
Show all
 296 aa
33.9 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.