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Malignancies displayed mainly weak to moderate cytoplasmic immunoreactivity. Malignant lymphoma, prostate, skin, testis and renal cancers were mostly negative.
GENE INFORMATION
Gene name
CDH22 (HGNC Symbol)
Synonyms
C20orf25, dJ998H6.1
Description
Cadherin 22, type 2 (HGNC Symbol)
Entrez gene summary
This gene is a member of the cadherin superfamily. The gene product is composed of five cadherin repeat domains and a cytoplasmic tail similar to the highly conserved cytoplasmic region of classical cadherins. Expressed predominantly in the brain, this putative calcium-dependent cell adhesion protein may play an important role in morphogenesis and tissue formation in neural and non-neural cells during development and maintenance of the brain and neuroendocrine organs. [provided by RefSeq, Jul 2008]