Expression of TMCO3 in cancer - Summary

CANCER ATLAS

Gene description

Transmembrane and coiled-coil domains 3

Protein class

Predicted intracellular proteins, Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA039561	HPA048126

GENE INFORMATION
Gene name	TMCO3 (HGNC Symbol)
Synonyms	C13orf11, FLJ20623
Description	Transmembrane and coiled-coil domains 3 (HGNC Symbol)
Entrez gene summary
Chromosome	13
Cytoband	q34
Chromosome location (bp)	113490995 - 113554590
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000150403 (version 83.38)
Entrez gene	55002
UniProt	Q6UWJ1 (UniProt - Evidence at transcript level)
neXtProt	NX_Q6UWJ1
Antibodypedia	TMCO3 antibodies

PROTEIN BROWSER

TMCO3-004	TMCO3-005	TMCO3-006	TMCO3-007	TMCO3-008	TMCO3-009	TMCO3-010

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TMCO3-004 ENSP00000481060 ENST00000462877	A0A087WXI4 [Direct mapping] Transmembrane and coiled-coil domain-containing protein 3 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0006812 [cation transport] GO:0015299 [solute:proton antiporter activity] GO:0016021 [integral component of membrane] GO:0055085 [transmembrane transport] GO:1902600 [hydrogen ion transmembrane transport] Show all	163 aa 17.9 kDa	No	2
TMCO3-005 ENSP00000478818 ENST00000473287	A0A087WUP6 [Direct mapping] Transmembrane and coiled-coil domain-containing protein 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		145 aa 16.8 kDa	No	0
TMCO3-006 ENSP00000484053 ENST00000474393	Q6UWJ1 [Direct mapping] Transmembrane and coiled-coil domain-containing protein 3 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0006812 [cation transport] GO:0015299 [solute:proton antiporter activity] GO:0016021 [integral component of membrane] GO:0055085 [transmembrane transport] GO:1902600 [hydrogen ion transmembrane transport] Show all	524 aa 58.9 kDa	Yes	7
TMCO3-007 ENSP00000389399 ENST00000434316	Q6UWJ1 [Direct mapping] Transmembrane and coiled-coil domain-containing protein 3 A0A024RE09 [Target identity:100%; Query identity:100%] Transmembrane and coiled-coil domains 3, isoform CRA_a Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0006812 [cation transport] GO:0015299 [solute:proton antiporter activity] GO:0016021 [integral component of membrane] GO:0055085 [transmembrane transport] GO:1902600 [hydrogen ion transmembrane transport] Show all	677 aa 75.6 kDa	Yes	>9
TMCO3-008 ENSP00000364540 ENST00000375391	Q6UWJ1 [Direct mapping] Transmembrane and coiled-coil domain-containing protein 3 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0006812 [cation transport] GO:0015299 [solute:proton antiporter activity] GO:0016021 [integral component of membrane] GO:0055085 [transmembrane transport] GO:1902600 [hydrogen ion transmembrane transport] Show all	414 aa 46.8 kDa	Yes	4
TMCO3-009 ENSP00000482311 ENST00000622371	A0A087WZ28 [Direct mapping] Transmembrane and coiled-coil domain-containing protein 3 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0006812 [cation transport] GO:0015299 [solute:proton antiporter activity] GO:0016021 [integral component of membrane] GO:0055085 [transmembrane transport] GO:1902600 [hydrogen ion transmembrane transport] Show all	126 aa 13.9 kDa	No	2
TMCO3-010 ENSP00000479613 ENST00000620021	A0A087WVR2 [Direct mapping] Transmembrane and coiled-coil domain-containing protein 3 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0006812 [cation transport] GO:0015299 [solute:proton antiporter activity] GO:0016021 [integral component of membrane] GO:0055085 [transmembrane transport] GO:1902600 [hydrogen ion transmembrane transport] Show all	94 aa 10.3 kDa	Yes	1