Expression of PRSS23 in cancer - Summary

CANCER ATLAS

Gene description

Protease, serine, 23

Protein class

Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA030591

GENE INFORMATION
Gene name	PRSS23 (HGNC Symbol)
Synonyms	SIG13, SPUVE
Description	Protease, serine, 23 (HGNC Symbol)
Entrez gene summary	This gene encodes a conserved member of the trypsin family of serine proteases. Mouse studies found a decrease of mRNA levels of this gene after ovulation was induced. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]
Chromosome	11
Cytoband	q14.2
Chromosome location (bp)	86791059 - 86952910
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000150687 (version 83.38)
Entrez gene	11098
UniProt	O95084 (UniProt - Evidence at protein level)
neXtProt	NX_O95084
Antibodypedia	PRSS23 antibodies

PROTEIN BROWSER

PRSS23-001	PRSS23-004	PRSS23-005

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PRSS23-001 ENSP00000280258 ENST00000280258	O95084 [Direct mapping] Serine protease 23 Show all	Enzymes Peptidases Serine-type peptidases MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004252 [serine-type endopeptidase activity] GO:0005634 [nucleus] GO:0006508 [proteolysis] GO:0070062 [extracellular exosome] Show all	383 aa 43 kDa	Yes	0
PRSS23-004 ENSP00000437268 ENST00000533902	E9PMX2 [Direct mapping] Serine protease 23 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		91 aa 10.3 kDa	No	0
PRSS23-005 ENSP00000435951 ENST00000527521	E9PRR2 [Direct mapping] Serine protease 23 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all		154 aa 16.9 kDa	Yes	0