Tissue expression of PPP1R1C - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	PPP1R1C
Gene description	Protein phosphatase 1, regulatory (inhibitor) subunit 1C
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enriched (heart muscle)
GTEx:	Group enriched (testis, heart muscle)
FANTOM5:	Tissue enhanced (testis, heart muscle)

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (heart muscle)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Group enriched (testis, heart muscle)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (testis, heart muscle)

GENE INFORMATION
Gene name	PPP1R1C (HGNC Symbol)
Synonyms	Inhibitor-1-like
Description	Protein phosphatase 1, regulatory (inhibitor) subunit 1C (HGNC Symbol)
Entrez gene summary	Protein phosphatase-1 (PP1) is a major serine/threonine phosphatase that regulates a variety of cellular functions. PP1 consists of a catalytic subunit (see PPP1CA; MIM 176875) and regulatory subunits that determine the subcellular localization of PP1 or regulate its function. PPP1R1C belongs to a group of PP1 inhibitory subunits that are themselves regulated by phosphorylation (Wang et al., 2008 [PubMed 18310074]).[supplied by OMIM, Feb 2010]
Chromosome	2
Cytoband
Chromosome location (bp)	181954241 - 182131398
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000150722 (version 83.38)
Entrez gene	151242
UniProt	Q8WVI7 (UniProt - Evidence at protein level)
neXtProt	NX_Q8WVI7
Antibodypedia	PPP1R1C antibodies

PROTEIN BROWSER

PPP1R1C-003	PPP1R1C-004	PPP1R1C-005

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PPP1R1C-003 ENSP00000386359 ENST00000409137	Q8WVI7 [Direct mapping] Protein phosphatase 1 regulatory subunit 1C Show all	Predicted intracellular proteins Show all	GO:0004864 [protein phosphatase inhibitor activity] GO:0004865 [protein serine/threonine phosphatase inhibitor activity] GO:0005737 [cytoplasm] GO:0006469 [negative regulation of protein kinase activity] GO:0007049 [cell cycle] GO:0007165 [signal transduction] GO:0030307 [positive regulation of cell growth] GO:0035556 [intracellular signal transduction] GO:0051301 [cell division] GO:1900087 [positive regulation of G1/S transition of mitotic cell cycle] Show all	109 aa 12.3 kDa	No	0
PPP1R1C-004 ENSP00000280295 ENST00000280295	Q8WVI7 [Direct mapping] Protein phosphatase 1 regulatory subunit 1C Show all	Predicted intracellular proteins Show all	GO:0004864 [protein phosphatase inhibitor activity] GO:0004865 [protein serine/threonine phosphatase inhibitor activity] GO:0005737 [cytoplasm] GO:0006469 [negative regulation of protein kinase activity] GO:0007049 [cell cycle] GO:0007165 [signal transduction] GO:0030307 [positive regulation of cell growth] GO:0035556 [intracellular signal transduction] GO:0051301 [cell division] GO:1900087 [positive regulation of G1/S transition of mitotic cell cycle] Show all	116 aa 13.1 kDa	No	0
PPP1R1C-005 ENSP00000386778 ENST00000409702	Q8WVI7 [Direct mapping] Protein phosphatase 1 regulatory subunit 1C Show all	Predicted intracellular proteins Show all	GO:0004864 [protein phosphatase inhibitor activity] GO:0004865 [protein serine/threonine phosphatase inhibitor activity] GO:0005737 [cytoplasm] GO:0006469 [negative regulation of protein kinase activity] GO:0007049 [cell cycle] GO:0007165 [signal transduction] GO:0030307 [positive regulation of cell growth] GO:0035556 [intracellular signal transduction] GO:0051301 [cell division] GO:1900087 [positive regulation of G1/S transition of mitotic cell cycle] Show all	109 aa 12.3 kDa	No	0