Cell atlas - CRIM1 - The Human Protein Atlas

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CRIM1

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	CRIM1
Gene description	Cysteine rich transmembrane BMP regulator 1 (chordin-like)
Protein class	Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	4
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Cell line enhanced (TIME)
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (TIME) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	CRIM1 (HGNC Symbol)
Synonyms	S52
Description	Cysteine rich transmembrane BMP regulator 1 (chordin-like) (HGNC Symbol)
Entrez gene summary	This gene encodes a transmembrane protein containing six cysteine-rich repeat domains and an insulin-like growth factor-binding domain. The encoded protein may play a role in tissue development though interactions with members of the transforming growth factor beta family, such as bone morphogenetic proteins. [provided by RefSeq, Nov 2010]
Chromosome	2
Cytoband	p22.2
Chromosome location (bp)	36355926 - 36551135
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000150938 (version 83.38)
Entrez gene	51232
UniProt	Q9NZV1 (UniProt - Evidence at protein level)
neXtProt	NX_Q9NZV1
Antibodypedia	CRIM1 antibodies

PROTEIN BROWSER

CRIM1-001	CRIM1-002	CRIM1-006	CRIM1-008

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CRIM1-001 ENSP00000280527 ENST00000280527	Q9NZV1 [Direct mapping] Cysteine-rich motor neuron 1 protein Processed cysteine-rich motor neuron 1 protein Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0001558 [regulation of cell growth] GO:0004857 [enzyme inhibitor activity] GO:0004867 [serine-type endopeptidase inhibitor activity] GO:0005010 [insulin-like growth factor-activated receptor activity] GO:0005515 [protein binding] GO:0005520 [insulin-like growth factor binding] GO:0005576 [extracellular region] GO:0005886 [plasma membrane] GO:0007399 [nervous system development] GO:0010951 [negative regulation of endopeptidase activity] GO:0016021 [integral component of membrane] GO:0030165 [PDZ domain binding] GO:0048009 [insulin-like growth factor receptor signaling pathway] GO:0070062 [extracellular exosome] Show all	1036 aa 113.7 kDa	Yes	1
CRIM1-002 ENSP00000415706 ENST00000428774	H7C458 [Direct mapping] Cysteine-rich motor neuron 1 protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0001558 [regulation of cell growth] GO:0005520 [insulin-like growth factor binding] GO:0005576 [extracellular region] Show all	55 aa 5.7 kDa	No	0
CRIM1-006 ENSP00000407636 ENST00000426856	H7C2T6 [Direct mapping] Cysteine-rich motor neuron 1 protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0001558 [regulation of cell growth] GO:0005520 [insulin-like growth factor binding] GO:0005576 [extracellular region] Show all	222 aa 23.5 kDa	No	0
CRIM1-008 ENSP00000403120 ENST00000413985	H7C1Z0 [Direct mapping] Cysteine-rich motor neuron 1 protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	175 aa 18.9 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.