Expression of GPR158 in cancer - Summary

CANCER ATLAS

Gene description

G protein-coupled receptor 158

Protein class

G-protein coupled receptors, Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA013185

GENE INFORMATION
Gene name	GPR158 (HGNC Symbol)
Synonyms	KIAA1136
Description	G protein-coupled receptor 158 (HGNC Symbol)
Entrez gene summary
Chromosome	10
Cytoband	p12.1
Chromosome location (bp)	25175062 - 25602226
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000151025 (version 83.38)
Entrez gene	57512
UniProt	Q5T848 (UniProt - Evidence at protein level)
neXtProt	NX_Q5T848
Antibodypedia	GPR158 antibodies

PROTEIN BROWSER

GPR158-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GPR158-001 ENSP00000365529 ENST00000376351	Q5T848 [Direct mapping] Probable G-protein coupled receptor 158 Show all	Family 3 (C) receptors G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0004930 [G-protein coupled receptor activity] GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0008277 [regulation of G-protein coupled receptor protein signaling pathway] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0072659 [protein localization to plasma membrane] Show all	1215 aa 135.5 kDa	Yes	7