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IPMK

GENERAL INFORMATION

Gene name

 IPMK

Gene description

 Inositol polyphosphate multikinase

Protein class

 Enzymes
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Mixed
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression in most tissues.

DATA RELIABILITY

Data reliability
description

 Pending external verification.

Reliability score

 Uncertain based on 1 antibody.
HPA037837
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 IPMK

Synonyms

Description

 Inositol polyphosphate multikinase (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the inositol phosphokinase family. The encoded protein has 3-kinase, 5-kinase and 6-kinase activities on phosphorylated inositol substrates. The encoded protein plays an important role in the biosynthesis of inositol 1,3,4,5,6-pentakisphosphate, and has a preferred 5-kinase activity. This gene may play a role in nuclear mRNA export. Pseudogenes of this gene are located on the long arm of chromosome 13 and the short arm of chromosome 19. [provided by RefSeq, Dec 2010]

Chromosome

 10

Cytoband

 q21.1

Chromosome location (bp)

 58191517 - 58267934

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000151151 (version 83.38)

Entrez gene

 253430

UniProt

 Q8NFU5 (UniProt - Evidence at protein level)

neXtProt

 NX_Q8NFU5

Antibodypedia

 IPMK antibodies

PROTEIN BROWSER
IPMK-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
IPMK-001
ENSP00000363046
ENST00000373935
Q8NFU5 [Direct mapping]
Inositol polyphosphate multikinase
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Enzymes
   ENZYME proteins
   Transferases
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000823 [inositol-1,4,5-trisphosphate 6-kinase activity]
GO:0000824 [inositol tetrakisphosphate 3-kinase activity]
GO:0001841 [neural tube formation]
GO:0005524 [ATP binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005730 [nucleolus]
GO:0008440 [inositol-1,4,5-trisphosphate 3-kinase activity]
GO:0016310 [phosphorylation]
GO:0032958 [inositol phosphate biosynthetic process]
GO:0043647 [inositol phosphate metabolic process]
GO:0044281 [small molecule metabolic process]
Show all
 416 aa
47.2 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.