Tissue expression of MIPOL1 - Summary - The Human Protein Atlas

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MIPOL1

TISSUE

CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	MIPOL1
Gene description	Mirror-image polydactyly 1
Protein class	Disease related genes Plasma proteins Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	8
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Mixed
GTEx:	Mixed
FANTOM5:	Mixed

Protein evidence

Evidence at protein level

Protein expression

General cytoplasmic expression.

DATA RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data.
Reliability score	Approved based on 1 antibody. HPA002893
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Mixed
GTEx dataset Organ Expression Alphabetical RNA tissue category: Mixed
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Mixed

GENE INFORMATION
Gene name	MIPOL1
Synonyms
Description	Mirror-image polydactyly 1 (HGNC Symbol)
Entrez gene summary	This gene encodes a coiled-coil domain-containing protein. The encoded protein may function as a tumor suppressor. A translocation that results in truncation of the protein encoded by this locus has been associated with mirror-image polydactyly, also known as Laurin-Sandrow Syndrome. Alternatively spliced transcript variants have been described. [provided by RefSeq, Sep 2010]
Chromosome	14
Cytoband
Chromosome location (bp)	37197913 - 37552361
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000151338 (version 83.38)
Entrez gene	145282
UniProt	Q8TD10 (UniProt - Evidence at protein level)
neXtProt	NX_Q8TD10
Antibodypedia	MIPOL1 antibodies

PROTEIN BROWSER

MIPOL1-001	MIPOL1-002	MIPOL1-003	MIPOL1-011	MIPOL1-012	MIPOL1-201	MIPOL1-202	MIPOL1-203

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
MIPOL1-001 ENSP00000333539 ENST00000327441	Q8TD10 [Direct mapping] Mirror-image polydactyly gene 1 protein Show all	Predicted intracellular proteins Plasma proteins Disease related genes Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] Show all	442 aa 51.5 kDa	No	0
MIPOL1-002 ENSP00000450479 ENST00000556451	Q49AL5 [Direct mapping] MIPOL1 protein; Mirror-image polydactyly 1, isoform CRA_a; Mirror-image polydactyly gene 1 protein Show all	Predicted intracellular proteins Show all		424 aa 49.7 kDa	No	0
MIPOL1-003 ENSP00000438319 ENST00000539062	G5EA54 [Direct mapping] Mirror-image polydactyly 1, isoform CRA_b; Mirror-image polydactyly gene 1 protein Show all	Predicted intracellular proteins Show all		411 aa 47.9 kDa	No	0
MIPOL1-011 ENSP00000451297 ENST00000556615	G3V3K8 [Direct mapping] Mirror-image polydactyly gene 1 protein Show all	Predicted intracellular proteins Show all		104 aa 12.3 kDa	No	0
MIPOL1-012 ENSP00000450575 ENST00000556753	G3V2C4 [Direct mapping] Mirror-image polydactyly gene 1 protein Show all	Predicted intracellular proteins Show all		128 aa 15 kDa	No	0
MIPOL1-201 ENSP00000379589 ENST00000396294	Q8TD10 [Direct mapping] Mirror-image polydactyly gene 1 protein Show all	Predicted intracellular proteins Plasma proteins Disease related genes Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] Show all	442 aa 51.5 kDa	No	0
MIPOL1-202 ENSP00000444254 ENST00000537471	Q8TD10 [Direct mapping] Mirror-image polydactyly gene 1 protein Show all	Predicted intracellular proteins Plasma proteins Disease related genes Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] Show all	442 aa 51.5 kDa	No	0
MIPOL1-203 ENSP00000442529 ENST00000545536	Q49AL5 [Direct mapping] MIPOL1 protein; Mirror-image polydactyly 1, isoform CRA_a; Mirror-image polydactyly gene 1 protein Show all	Predicted intracellular proteins Show all		424 aa 49.7 kDa	No	0

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.