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Several cases of ovarian, prostate, breast, endometrial and liver cancers showed moderate cytoplasmic immunoreactivity. Most of the remaining cancer tissues were weakly stained or negative.
GENE INFORMATION
Gene name
NUBPL (HGNC Symbol)
Synonyms
C14orf127, FLJ12660, huInd1, IND1
Description
Nucleotide binding protein-like (HGNC Symbol)
Entrez gene summary
This gene encodes a member of the Mrp/NBP35 ATP-binding proteins family. The encoded protein is required for the assembly of the respiratory chain NADH dehydrogenase (complex I), an oligomeric enzymatic complex located in the inner mitochondrial membrane. Mutations in this gene cause mitochondrial complex I deficiency. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
Q8TB37 [Direct mapping] Iron-sulfur protein NUBPL X5D2R5 [Target identity:100%; Query identity:100%] Nucleotide binding protein-like isoform A
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Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
