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SCLT1

CANCER ATLAS

Gene description

 Sodium channel and clathrin linker 1

Protein class

 Predicted intracellular proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA036560
HPA036561

GENE INFORMATION

Gene name

 SCLT1 (HGNC Symbol)

Synonyms

 FLJ30655, hCAP-1A

Description

 Sodium channel and clathrin linker 1 (HGNC Symbol)

Entrez gene summary

 This gene encodes an adaptor protein. Studies of a related gene in rat suggest that the encoded protein functions to link clathrin to the sodium channel protein type 10 subunit alpha protein. The encoded protein has also been identified as a component of distal appendages of centrioles that is necessary for ciliogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

Chromosome

 4

Cytoband

 q28.2

Chromosome location (bp)

 128864921 - 129093607

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000151466 (version 83.38)

Entrez gene

 132320

UniProt

 Q96NL6 (UniProt - Evidence at protein level)

neXtProt

 NX_Q96NL6

Antibodypedia

 SCLT1 antibodies

PROTEIN BROWSER
SCLT1-001
SCLT1-002
SCLT1-003
SCLT1-004
SCLT1-005
SCLT1-008

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
SCLT1-001
ENSP00000281142
ENST00000281142
Q96NL6 [Direct mapping]
Sodium channel and clathrin linker 1
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005813 [centrosome]
GO:0005814 [centriole]
GO:0005829 [cytosol]
GO:0006996 [organelle organization]
GO:0008022 [protein C-terminus binding]
GO:0017080 [sodium channel regulator activity]
GO:0030276 [clathrin binding]
GO:0042384 [cilium assembly]
GO:0045162 [clustering of voltage-gated sodium channels]
GO:0070062 [extracellular exosome]
GO:0071439 [clathrin complex]
GO:0097539 [ciliary transition fiber]
Show all
 688 aa
80.9 kDa 		No 0
SCLT1-002
ENSP00000425315
ENST00000503401
D6RDM2 [Direct mapping]
Sodium channel and clathrin linker 1
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 56 aa
6.4 kDa 		No 0
SCLT1-003
ENSP00000420861
ENST00000511426
Q96NL6 [Direct mapping]
Sodium channel and clathrin linker 1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005813 [centrosome]
GO:0005814 [centriole]
GO:0005829 [cytosol]
GO:0006996 [organelle organization]
GO:0042384 [cilium assembly]
GO:0070062 [extracellular exosome]
GO:0097539 [ciliary transition fiber]
Show all
 79 aa
9.3 kDa 		No 0
SCLT1-004
ENSP00000395292
ENST00000439369
Q96NL6 [Direct mapping]
Sodium channel and clathrin linker 1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005813 [centrosome]
GO:0005814 [centriole]
GO:0005829 [cytosol]
GO:0006996 [organelle organization]
GO:0042384 [cilium assembly]
GO:0070062 [extracellular exosome]
GO:0097539 [ciliary transition fiber]
Show all
 175 aa
20.5 kDa 		No 0
SCLT1-005
ENSP00000424029
ENST00000503215
D6RBP0 [Direct mapping]
Sodium channel and clathrin linker 1
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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 284 aa
33.1 kDa 		No 0
SCLT1-008
ENSP00000424304
ENST00000506368
D6RBA6 [Direct mapping]
Sodium channel and clathrin linker 1
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 131 aa
15.2 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.