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BICD1

GENERAL INFORMATION

Gene name

 BICD1

Gene description

 Bicaudal D homolog 1 (Drosophila)

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 7
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Mixed
GTEx:Mixed
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Estimation of protein expression could not be performed. View primary data.

DATA RELIABILITY

Data reliability
description

 RNA-based expert annotation gave inconclusive results.

Reliability score

 Uncertain based on 1 antibody.
HPA041309
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
N/A
Hippocampus
N/A
N/A
Caudate
N/A
N/A
Cerebellum
N/A
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Appendix
N/A
Tonsil
N/A
Spleen
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Oral mucosa
N/A
N/A
Esophagus
N/A
Stomach
N/A
Duodenum
N/A
Colon
N/A
Rectum
N/A
Kidney & urinary bladder
N/A
Kidney
N/A
Male tissues
N/A
Testis
N/A
Prostate
N/A
Female tissues
N/A
Breast
N/A
Vagina
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Soft tissue
N/A
N/A
Skin
N/A
Skin
N/A
Cerebral cortex

Lymph node

Skeletal muscle

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 BICD1

Synonyms

Description

 Bicaudal D homolog 1 (Drosophila) (HGNC Symbol)

Entrez gene summary

 This gene is one of two human homologs of Drosophila bicaudal-D. It has been implicated in COPI-independent membrane transport from the Golgi apparatus to the endoplasmic reticulum. Two alternative splice variants have been described. Other alternative splice variants that encode different protein isoforms have been described but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]

Chromosome

 12

Cytoband

 p11.21

Chromosome location (bp)

 32106835 - 32383633

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000151746 (version 83.38)

Entrez gene

 636

UniProt

 Q96G01 (UniProt - Evidence at protein level)

neXtProt

 NX_Q96G01

Antibodypedia

 BICD1 antibodies

PROTEIN BROWSER
BICD1-001
BICD1-002
BICD1-004
BICD1-005
BICD1-006
BICD1-007
BICD1-008

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
BICD1-001
ENSP00000446793
ENST00000548411
Q96G01 [Direct mapping]
Protein bicaudal D homolog 1
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005200 [structural constituent of cytoskeleton]
GO:0005515 [protein binding]
GO:0005794 [Golgi apparatus]
GO:0005802 [trans-Golgi network]
GO:0005829 [cytosol]
GO:0005856 [cytoskeleton]
GO:0005881 [cytoplasmic microtubule]
GO:0006396 [RNA processing]
GO:0006810 [transport]
GO:0008093 [cytoskeletal adaptor activity]
GO:0008298 [intracellular mRNA localization]
GO:0009653 [anatomical structure morphogenesis]
GO:0016020 [membrane]
GO:0016032 [viral process]
GO:0017137 [Rab GTPase binding]
GO:0031410 [cytoplasmic vesicle]
GO:0031871 [proteinase activated receptor binding]
GO:0033365 [protein localization to organelle]
GO:0034063 [stress granule assembly]
GO:0034452 [dynactin binding]
GO:0045298 [tubulin complex]
GO:0045502 [dynein binding]
GO:0048260 [positive regulation of receptor-mediated endocytosis]
GO:0048471 [perinuclear region of cytoplasm]
GO:0072385 [minus-end-directed organelle transport along microtubule]
GO:0072393 [microtubule anchoring at microtubule organizing center]
GO:0072517 [host cell viral assembly compartment]
GO:1900275 [negative regulation of phospholipase C activity]
GO:1900276 [regulation of proteinase activated receptor activity]
GO:1900737 [negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway]
Show all
 835 aa
95.7 kDa 		No 0
BICD1-002
ENSP00000281474
ENST00000281474
Q96G01 [Direct mapping]
Protein bicaudal D homolog 1
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005200 [structural constituent of cytoskeleton]
GO:0005515 [protein binding]
GO:0005794 [Golgi apparatus]
GO:0005802 [trans-Golgi network]
GO:0005829 [cytosol]
GO:0005856 [cytoskeleton]
GO:0005881 [cytoplasmic microtubule]
GO:0006396 [RNA processing]
GO:0006810 [transport]
GO:0008093 [cytoskeletal adaptor activity]
GO:0008298 [intracellular mRNA localization]
GO:0009653 [anatomical structure morphogenesis]
GO:0016020 [membrane]
GO:0016032 [viral process]
GO:0017137 [Rab GTPase binding]
GO:0031410 [cytoplasmic vesicle]
GO:0031871 [proteinase activated receptor binding]
GO:0033365 [protein localization to organelle]
GO:0034063 [stress granule assembly]
GO:0034452 [dynactin binding]
GO:0045298 [tubulin complex]
GO:0045502 [dynein binding]
GO:0048260 [positive regulation of receptor-mediated endocytosis]
GO:0048471 [perinuclear region of cytoplasm]
GO:0072385 [minus-end-directed organelle transport along microtubule]
GO:0072393 [microtubule anchoring at microtubule organizing center]
GO:0072517 [host cell viral assembly compartment]
GO:1900275 [negative regulation of phospholipase C activity]
GO:1900276 [regulation of proteinase activated receptor activity]
GO:1900737 [negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway]
Show all
 975 aa
110.7 kDa 		No 0
BICD1-004
ENSP00000481877
ENST00000552160
A0A087WYJ7 [Direct mapping]
Protein bicaudal D homolog 1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005794 [Golgi apparatus]
GO:0006810 [transport]
Show all
 173 aa
19.4 kDa 		No 0
BICD1-005
ENSP00000448933
ENST00000551848
Q96G01 [Direct mapping]
Protein bicaudal D homolog 1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005200 [structural constituent of cytoskeleton]
GO:0005515 [protein binding]
GO:0005794 [Golgi apparatus]
GO:0005802 [trans-Golgi network]
GO:0005829 [cytosol]
GO:0005856 [cytoskeleton]
GO:0005881 [cytoplasmic microtubule]
GO:0006396 [RNA processing]
GO:0008093 [cytoskeletal adaptor activity]
GO:0008298 [intracellular mRNA localization]
GO:0009653 [anatomical structure morphogenesis]
GO:0016020 [membrane]
GO:0016032 [viral process]
GO:0017137 [Rab GTPase binding]
GO:0031410 [cytoplasmic vesicle]
GO:0031871 [proteinase activated receptor binding]
GO:0033365 [protein localization to organelle]
GO:0034063 [stress granule assembly]
GO:0034452 [dynactin binding]
GO:0045298 [tubulin complex]
GO:0045502 [dynein binding]
GO:0048260 [positive regulation of receptor-mediated endocytosis]
GO:0048471 [perinuclear region of cytoplasm]
GO:0072385 [minus-end-directed organelle transport along microtubule]
GO:0072393 [microtubule anchoring at microtubule organizing center]
GO:0072517 [host cell viral assembly compartment]
GO:1900275 [negative regulation of phospholipase C activity]
GO:1900276 [regulation of proteinase activated receptor activity]
GO:1900737 [negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway]
Show all
 93 aa
10.7 kDa 		No 0
BICD1-006
ENSP00000447238
ENST00000551086
F8W056 [Direct mapping]
Protein bicaudal D homolog 1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005794 [Golgi apparatus]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006810 [transport]
GO:0043565 [sequence-specific DNA binding]
Show all
 93 aa
10.9 kDa 		No 0
BICD1-007
ENSP00000447663
ENST00000550207
F8VZX7 [Direct mapping]
Protein bicaudal D homolog 1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005794 [Golgi apparatus]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006810 [transport]
GO:0043565 [sequence-specific DNA binding]
Show all
 79 aa
9.3 kDa 		No 0
BICD1-008
ENSP00000475837
ENST00000547680
U3KQF7 [Direct mapping]
Protein bicaudal D homolog 1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005794 [Golgi apparatus]
GO:0006810 [transport]
Show all
 69 aa
7.6 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.