Expression of PARP8 in cancer - Summary

CANCER ATLAS

Gene description

Poly (ADP-ribose) polymerase family, member 8

Protein class

Enzymes, Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA049183

GENE INFORMATION
Gene name	PARP8 (HGNC Symbol)
Synonyms	FLJ21308, pART16
Description	Poly (ADP-ribose) polymerase family, member 8 (HGNC Symbol)
Entrez gene summary
Chromosome	5
Cytoband	q11.1
Chromosome location (bp)	50665899 - 50846522
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000151883 (version 83.38)
Entrez gene	79668
UniProt	Q8N3A8 (UniProt - Evidence at transcript level)
neXtProt	NX_Q8N3A8
Antibodypedia	PARP8 antibodies

PROTEIN BROWSER

PARP8-001	PARP8-002	PARP8-004	PARP8-007	PARP8-012	PARP8-017	PARP8-019	PARP8-020	PARP8-026	PARP8-201	PARP8-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PARP8-001 ENSP00000281631 ENST00000281631	Q8N3A8 [Direct mapping] Poly [ADP-ribose] polymerase 8 Show all	Enzymes ENZYME proteins Transferases Predicted intracellular proteins Show all	GO:0003950 [NAD+ ADP-ribosyltransferase activity] GO:0005622 [intracellular] GO:0008152 [metabolic process] Show all	854 aa 95.9 kDa	No	0
PARP8-002 ENSP00000422217 ENST00000505697	Q8N3A8 [Direct mapping] Poly [ADP-ribose] polymerase 8 Show all	Enzymes ENZYME proteins Transferases Predicted intracellular proteins Show all	GO:0003950 [NAD+ ADP-ribosyltransferase activity] GO:0005622 [intracellular] GO:0008152 [metabolic process] Show all	854 aa 95.9 kDa	No	0
PARP8-004 ENSP00000424814 ENST00000514067	Q8N3A8 [Direct mapping] Poly [ADP-ribose] polymerase 8 Show all	Enzymes ENZYME proteins Transferases Predicted intracellular proteins Show all	GO:0003950 [NAD+ ADP-ribosyltransferase activity] GO:0005622 [intracellular] GO:0008152 [metabolic process] Show all	812 aa 91.2 kDa	No	0
PARP8-007 ENSP00000423946 ENST00000505554	E9PFI7 [Direct mapping] Poly [ADP-ribose] polymerase 8 Show all	Predicted intracellular proteins Show all	GO:0003950 [NAD+ ADP-ribosyltransferase activity] GO:0008152 [metabolic process] Show all	833 aa 93.4 kDa	No	0
PARP8-012 ENSP00000426243 ENST00000502524	D6RGZ9 [Direct mapping] Poly [ADP-ribose] polymerase 8 Show all	Predicted intracellular proteins Show all		77 aa 8.8 kDa	No	0
PARP8-017 ENSP00000422355 ENST00000513738	D6RC81 [Direct mapping] Poly [ADP-ribose] polymerase 8 Show all	Predicted intracellular proteins Show all		133 aa 14.9 kDa	No	0
PARP8-019 ENSP00000427138 ENST00000503665	D6RCN2 [Direct mapping] Poly [ADP-ribose] polymerase 8 Show all	Predicted intracellular proteins Show all		57 aa 6.6 kDa	No	0
PARP8-020 ENSP00000423133 ENST00000515175	D6R9T2 [Direct mapping] Poly [ADP-ribose] polymerase 8 Show all	Predicted intracellular proteins Show all		64 aa 7.4 kDa	No	0
PARP8-026 ENSP00000421708 ENST00000503046	D6RAL6 [Direct mapping] Poly [ADP-ribose] polymerase 8 Show all	Predicted intracellular proteins Show all		116 aa 13.2 kDa	No	0
PARP8-201 ENSP00000440851 ENST00000503750	A0A0A0MTI7 [Direct mapping] Poly [ADP-ribose] polymerase 8 Show all	Predicted intracellular proteins Show all	GO:0003950 [NAD+ ADP-ribosyltransferase activity] GO:0008152 [metabolic process] Show all	493 aa 55 kDa	No	0
PARP8-202 ENSP00000439022 ENST00000514342	F5H3X8 [Direct mapping] Poly [ADP-ribose] polymerase 8 Show all	Predicted intracellular proteins Show all	GO:0003950 [NAD+ ADP-ribosyltransferase activity] GO:0008152 [metabolic process] Show all	494 aa 55.1 kDa	No	0