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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Tissue

Detectable

Cell line

Detectable

Category

Score

Score

Score

Antibodies

Column

 
 
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RNF219
  • premium

    TISSUE

  • CELL

  • CANCER

CANCER ATLAS

GENE/PROTEIN

Antibody validation

Dictionary

Level of antibody staining/expression





High
Medium
Low
Not detected

CANCER ATLAS

Gene description

Ring finger protein 219

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer

STAINING SUMMARY

HPA034785
HPA034786

Tissue

Cancer staining

Protein
expression of
normal tissue

Breast cancer
 
Carcinoid
 
Cervical cancer
 
 
Colorectal cancer
 
 
Endometrial cancer
 
 
Glioma
 
Head and neck cancer
 
 
Liver cancer
 
 
Lung cancer
 
 
Lymphoma
 
 
 

Tissue

Cancer staining

Protein
expression of
normal tissue

Melanoma
 
Ovarian cancer
 
Pancreatic cancer
 
Prostate cancer
 
Renal cancer
 
Skin cancer
 
Stomach cancer
 
 
Testis cancer
 
Thyroid cancer
 
Urothelial cancer
 

Staining summary

A majority of cancer cells displayed weak to moderate cytoplasmic immunoreactivity. Most squamous cell carcinomas, renal, pancreatic and urothelial cancers were negative.

Tissue

Cancer staining

Protein
expression of
normal tissue

Breast cancer
 
Carcinoid
 
Cervical cancer
 
 
Colorectal cancer
 
 
Endometrial cancer
 
 
Glioma
 
Head and neck cancer
 
 
Liver cancer
 
 
Lung cancer
 
 
Lymphoma
 
 
 

Tissue

Cancer staining

Protein
expression of
normal tissue

Melanoma
 
Ovarian cancer
 
Pancreatic cancer
 
Prostate cancer
 
Renal cancer
 
Skin cancer
 
Stomach cancer
 
 
Testis cancer
 
Thyroid cancer
 
Urothelial cancer
 

Staining summary

Cancer tissues showed weak to moderate cytoplasmic positivity with additional nuclear staining in many cases.

GENE INFORMATION

Gene name

RNF219 (HGNC Symbol)

Synonyms

C13orf7, FLJ13449

Description

Ring finger protein 219 (HGNC Symbol)

Entrez gene summary

Chromosome

13

Cytoband

q31.1

Chromosome location (bp)

78614291 - 78659179

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000152193 (version 83.38)

Entrez gene

79596

UniProt

Q5W0B1 (UniProt - Evidence at protein level)

neXtProt

NX_Q5W0B1

Antibodypedia

RNF219 antibodies

PROTEIN BROWSER

RNF219-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

RNF219-001
ENSP00000282003
ENST00000282003
Q5W0B1 [Direct mapping]
RING finger protein 219
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0008270 [zinc ion binding]
GO:0048026 [positive regulation of mRNA splicing, via spliceosome]
Show all
726 aa
81.1 kDa
No 0

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