Expression of ARL14EP in cancer - Summary

CANCER ATLAS

Gene description

ADP-ribosylation factor-like 14 effector protein

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Glioma

STAINING SUMMARY

HPA039634	HPA048127

GENE INFORMATION
Gene name	ARL14EP (HGNC Symbol)
Synonyms	ARF7EP, C11orf46, FLJ38968
Description	ADP-ribosylation factor-like 14 effector protein (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is an effector protein. It interacts with ADP-ribosylation factor-like 14 [ARL14, also known as ADP-ribosylation factor 7 (ARF7)], beta-actin (ACTB) and actin-based motor protein myosin 1E (MYO1E). ARL14 is a small GTPase; it controls the export of major histocompatibility class II molecules by connecting to the actin network via this effector protein. [provided by RefSeq, Sep 2014]
Chromosome	11
Cytoband	p14.1
Chromosome location (bp)	30323051 - 30338227
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000152219 (version 83.38)
Entrez gene	120534
UniProt	Q8N8R7 (UniProt - Evidence at protein level)
neXtProt	NX_Q8N8R7
Antibodypedia	ARL14EP antibodies

PROTEIN BROWSER

ARL14EP-001	ARL14EP-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ARL14EP-001 ENSP00000282032 ENST00000282032	Q8N8R7 [Direct mapping] ARL14 effector protein Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005737 [cytoplasm] Show all	260 aa 29.3 kDa	No	0
ARL14EP-003 ENSP00000432224 ENST00000530909	E9PRK7 [Direct mapping] ARL14 effector protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		168 aa 19.1 kDa	No	0