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SH2D6

CANCER ATLAS

Gene description

 SH2 domain containing 6

Protein class

 Predicted intracellular proteins

Protein evidence

 Evidence at transcript level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA053873

GENE INFORMATION

Gene name

 SH2D6 (HGNC Symbol)

Synonyms

 FLJ35993

Description

 SH2 domain containing 6 (HGNC Symbol)

Entrez gene summary

Chromosome

 2

Cytoband

 p11.2

Chromosome location (bp)

 85418721 - 85437029

Protein evidence

 Evidence at transcript level (all genes)

Ensembl

 ENSG00000152292 (version 83.38)

Entrez gene

 284948

UniProt

 Q7Z4S9 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q7Z4S9

Antibodypedia

 SH2D6 antibodies

PROTEIN BROWSER
SH2D6-001
SH2D6-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
SH2D6-001
ENSP00000341867
ENST00000340326
Q7Z4S9 [Direct mapping]
SH2 domain-containing protein 6
Show all
Predicted intracellular proteins
Show all
GO:0005068 [transmembrane receptor protein tyrosine kinase adaptor activity]
GO:0005070 [SH3/SH2 adaptor activity]
GO:0005737 [cytoplasm]
GO:0006955 [immune response]
GO:0007169 [transmembrane receptor protein tyrosine kinase signaling pathway]
GO:0009967 [positive regulation of signal transduction]
GO:0035556 [intracellular signal transduction]
Show all
 175 aa
19.3 kDa 		No 0
SH2D6-002
ENSP00000374588
ENST00000389938
Q7Z4S9 [Direct mapping]
SH2 domain-containing protein 6
Show all
Predicted intracellular proteins
Show all
GO:0005068 [transmembrane receptor protein tyrosine kinase adaptor activity]
GO:0005070 [SH3/SH2 adaptor activity]
GO:0005737 [cytoplasm]
GO:0006955 [immune response]
GO:0007169 [transmembrane receptor protein tyrosine kinase signaling pathway]
GO:0009967 [positive regulation of signal transduction]
GO:0035556 [intracellular signal transduction]
Show all
 143 aa
15.4 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.