Cell atlas - TADA1 - The Human Protein Atlas

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TADA1

TISSUE

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CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol
	Focal adhesion sites
	Nucleoplasm

Human cell
	Actin Filaments
	Cytosol
	Nucleoplasm

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GENERAL INFORMATION
Gene name	TADA1
Gene description	Transcriptional adaptor 1
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the nucleoplasm. In addition localized to the cytosol & focal adhesion sites.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoplasm (supported)
Additional location	In addition localized to the Focal adhesion sites (approved), Cytosol (approved)
Single-cell variation	Single-cell variation in protein expression observed.

DATA RELIABILITY
Reliability score	Supported based on 1 antibody. HPA028651
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the nucleoplasm. In addition localized to the cytosol & focal adhesion sites.

Main location

Nucleoplasm (supported)

Additional location

Focal adhesion sites (approved), Cytosol (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA028651	A-431	Nucleoplasm	Intensity
	HPA028651	A-431	Cytosol	Intensity
	HPA028651	U-2 OS	Nucleoplasm	Intensity
	HPA028651	U-2 OS	Cytosol	Intensity
	HPA028651	U-251 MG	Nucleoplasm	Intensity
			Focal adhesion sites
			Cytosol	Intensity

GENE INFORMATION
Gene name	TADA1 (HGNC Symbol)
Synonyms	ADA1, hADA1, HFI1, STAF42, TADA1L
Description	Transcriptional adaptor 1 (HGNC Symbol)
Entrez gene summary	TADA1L is a protein subunit of the human STAGA complex (SPT3; (MIM 602947)/TAF9 (MIM 600822)/GCN5 (MIM 602301) acetyltransferase complex), which is a chromatin-modifying multiprotein complex (Martinez et al., 2001 [PubMed 11564863]).[supplied by OMIM, Apr 2009]
Chromosome	1
Cytoband	q24.1
Chromosome location (bp)	166856510 - 166876327
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000152382 (version 83.38)
Entrez gene	117143
UniProt	Q96BN2 (UniProt - Evidence at protein level)
neXtProt	NX_Q96BN2
Antibodypedia	TADA1 antibodies

PROTEIN BROWSER

TADA1-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TADA1-001 ENSP00000356848 ENST00000367874	Q96BN2 [Direct mapping] Transcriptional adapter 1 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003713 [transcription coactivator activity] GO:0004402 [histone acetyltransferase activity] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0005925 [focal adhesion] GO:0006325 [chromatin organization] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0030914 [STAGA complex] GO:0043966 [histone H3 acetylation] GO:0070461 [SAGA-type complex] Show all	335 aa 37.4 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.