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SUV39H2

CANCER ATLAS

Gene description

 Suppressor of variegation 3-9 homolog 2 (Drosophila)

Protein class

 Enzymes, Predicted intracellular proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer

STAINING SUMMARY
HPA057554

GENE INFORMATION

Gene name

 SUV39H2 (HGNC Symbol)

Synonyms

 FLJ23414, KMT1B

Description

 Suppressor of variegation 3-9 homolog 2 (Drosophila) (HGNC Symbol)

Entrez gene summary

Chromosome

 10

Cytoband

 p13

Chromosome location (bp)

 14878820 - 14904315

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000152455 (version 83.38)

Entrez gene

 79723

UniProt

 Q9H5I1 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9H5I1

Antibodypedia

 SUV39H2 antibodies

PROTEIN BROWSER
SUV39H2-001
SUV39H2-002
SUV39H2-003
SUV39H2-004
SUV39H2-005
SUV39H2-006
SUV39H2-008

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
SUV39H2-001
ENSP00000351046
ENST00000358298
H0Y306 [Direct mapping]
Histone-lysine N-methyltransferase SUV39H2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0008168 [methyltransferase activity]
GO:0032259 [methylation]
Show all
 176 aa
20 kDa 		No 0
SUV39H2-002
ENSP00000346997
ENST00000354919
Q9H5I1 [Direct mapping]
Histone-lysine N-methyltransferase SUV39H2
Show all
Enzymes
   ENZYME proteins
   Transferases
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0000775 [chromosome, centromeric region]
GO:0000785 [chromatin]
GO:0000976 [transcription regulatory region sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0006325 [chromatin organization]
GO:0006333 [chromatin assembly or disassembly]
GO:0006338 [chromatin remodeling]
GO:0006351 [transcription, DNA-templated]
GO:0007049 [cell cycle]
GO:0008270 [zinc ion binding]
GO:0018024 [histone-lysine N-methyltransferase activity]
GO:0030154 [cell differentiation]
GO:0034968 [histone lysine methylation]
GO:0036123 [histone H3-K9 dimethylation]
GO:0036124 [histone H3-K9 trimethylation]
GO:0042754 [negative regulation of circadian rhythm]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0046974 [histone methyltransferase activity (H3-K9 specific)]
GO:0048511 [rhythmic process]
GO:0071456 [cellular response to hypoxia]
Show all
 410 aa
46.7 kDa 		No 0
SUV39H2-003
ENSP00000388968
ENST00000433779
Q5JSS2 [Direct mapping]
Histone-lysine N-methyltransferase SUV39H2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005634 [nucleus]
Show all
 152 aa
17.6 kDa 		No 0
SUV39H2-004
ENSP00000392201
ENST00000420416
C9IYH9 [Direct mapping]
Histone-lysine N-methyltransferase SUV39H2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005634 [nucleus]
GO:0008270 [zinc ion binding]
GO:0018024 [histone-lysine N-methyltransferase activity]
GO:0034968 [histone lysine methylation]
Show all
 221 aa
25.4 kDa 		No 0
SUV39H2-005
ENSP00000388218
ENST00000412254
C9JMB4 [Direct mapping]
Histone-lysine N-methyltransferase SUV39H2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005634 [nucleus]
Show all
 96 aa
11.5 kDa 		No 0
SUV39H2-006
ENSP00000367576
ENST00000378325
Q9H5I1 [Direct mapping]
Histone-lysine N-methyltransferase SUV39H2
Show all
Enzymes
   ENZYME proteins
   Transferases
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0000775 [chromosome, centromeric region]
GO:0000785 [chromatin]
GO:0000976 [transcription regulatory region sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0006325 [chromatin organization]
GO:0006333 [chromatin assembly or disassembly]
GO:0006338 [chromatin remodeling]
GO:0006351 [transcription, DNA-templated]
GO:0007049 [cell cycle]
GO:0008270 [zinc ion binding]
GO:0018024 [histone-lysine N-methyltransferase activity]
GO:0030154 [cell differentiation]
GO:0034968 [histone lysine methylation]
GO:0036123 [histone H3-K9 dimethylation]
GO:0036124 [histone H3-K9 trimethylation]
GO:0042754 [negative regulation of circadian rhythm]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0046974 [histone methyltransferase activity (H3-K9 specific)]
GO:0048511 [rhythmic process]
GO:0071456 [cellular response to hypoxia]
Show all
 230 aa
26.3 kDa 		No 0
SUV39H2-008
ENSP00000319208
ENST00000313519
Q9H5I1 [Direct mapping]
Histone-lysine N-methyltransferase SUV39H2
Show all
Enzymes
   ENZYME proteins
   Transferases
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0000775 [chromosome, centromeric region]
GO:0000785 [chromatin]
GO:0000976 [transcription regulatory region sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0006325 [chromatin organization]
GO:0006333 [chromatin assembly or disassembly]
GO:0006338 [chromatin remodeling]
GO:0006351 [transcription, DNA-templated]
GO:0007049 [cell cycle]
GO:0008270 [zinc ion binding]
GO:0018024 [histone-lysine N-methyltransferase activity]
GO:0030154 [cell differentiation]
GO:0034968 [histone lysine methylation]
GO:0036123 [histone H3-K9 dimethylation]
GO:0036124 [histone H3-K9 trimethylation]
GO:0042754 [negative regulation of circadian rhythm]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0046974 [histone methyltransferase activity (H3-K9 specific)]
GO:0048511 [rhythmic process]
GO:0071456 [cellular response to hypoxia]
Show all
 350 aa
39.9 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.