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A few cases of prostate cancers showed moderate to strong cytoplasmic staining. Remaining cancer tissues were negative.
GENE INFORMATION
Gene name
CCNO (HGNC Symbol)
Synonyms
CCNU, FLJ22422, UDG2, UNG2
Description
Cyclin O (HGNC Symbol)
Entrez gene summary
This gene encodes a member of the cyclin protein family, and the encoded protein is involved in regulation of the cell cycle. Disruption of this gene is associated with primary ciliary dyskinesia-19. Alternative splicing results in multiple transcript variants. This gene, which has a previous symbol of UNG2, was erroneously identified as a uracil DNA glycosylase in PubMed ID: 2001396. A later publication, PubMed ID: 8419333, identified this gene's product as a cyclin protein family member. The UNG2 symbol is also used as a specific protein isoform name for the UNG gene (GeneID 7374), so confusion exists in the scientific literature and in some databases for these two genes. [provided by RefSeq, Jul 2014]
