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Several malignant melanomas and lung cancers along with a few malignant gliomas, ovarian, endometrial and liver cancers displayed moderate cytoplasmic positivity. Nuclear staining was observed in several cases. Remaining cancer cells were in general weakly stained or negative.
GENE INFORMATION
Gene name
GPR180 (HGNC Symbol)
Synonyms
ITR
Description
G protein-coupled receptor 180 (HGNC Symbol)
Entrez gene summary
This gene encodes a protein that is a member of the G protein-coupled receptor superfamily. This protein is produced predominantly in vascular smooth muscle cells and may play an important role in the regulation of vascular remodeling. [provided by RefSeq, Jul 2008]