Tissue expression of BMP3 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	BMP3
Gene description	Bone morphogenetic protein 3
Protein class	Plasma proteins Predicted secreted proteins
Predicted localization	Secreted
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enhanced (urinary bladder)
GTEx:	Tissue enhanced (colon, urinary bladder, small intestine)
FANTOM5:	Tissue enhanced (colon, small intestine, lung)

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (urinary bladder)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (colon, urinary bladder, small intestine)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (colon, small intestine, lung)

GENE INFORMATION
Gene name	BMP3
Synonyms
Description	Bone morphogenetic protein 3 (HGNC Symbol)
Entrez gene summary	BMP3 belongs to the transforming growth factor-beta (TGFB) superfamily. Bone morphogenic protein, also known as osteogenin, induces bone formation. [provided by RefSeq, Jul 2008]
Chromosome	4
Cytoband	q21.21
Chromosome location (bp)	81030965 - 81057531
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000152785 (version 83.38)
Entrez gene	651
UniProt	P12645 (UniProt - Evidence at protein level)
neXtProt	NX_P12645
Antibodypedia	BMP3 antibodies

PROTEIN BROWSER

BMP3-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
BMP3-001 ENSP00000282701 ENST00000282701	P12645 [Direct mapping] Bone morphogenetic protein 3 Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Show all	GO:0001501 [skeletal system development] GO:0001649 [osteoblast differentiation] GO:0005102 [receptor binding] GO:0005125 [cytokine activity] GO:0005160 [transforming growth factor beta receptor binding] GO:0005615 [extracellular space] GO:0007267 [cell-cell signaling] GO:0008083 [growth factor activity] GO:0010862 [positive regulation of pathway-restricted SMAD protein phosphorylation] GO:0040007 [growth] GO:0042981 [regulation of apoptotic process] GO:0043408 [regulation of MAPK cascade] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0048468 [cell development] GO:0051216 [cartilage development] GO:0060395 [SMAD protein signal transduction] GO:0070062 [extracellular exosome] GO:0070700 [BMP receptor binding] Show all	472 aa 53.4 kDa	Yes	0