Expression of RASSF3 in cancer - Summary

CANCER ATLAS

Gene description

Ras association (RalGDS/AF-6) domain family member 3

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA038469	CAB022664	CAB034035

GENE INFORMATION
Gene name	RASSF3
Synonyms
Description	Ras association (RalGDS/AF-6) domain family member 3 (HGNC Symbol)
Entrez gene summary	The RAS oncogene (MIM 190020) is mutated in nearly one-third of all human cancers. Members of the RAS superfamily are plasma membrane GTP-binding proteins that modulate intracellular signal transduction pathways. A subfamily of RAS effectors, including RASSF3, share a RAS association (RA) domain.[supplied by OMIM, Jul 2003]
Chromosome	12
Cytoband	q14.2
Chromosome location (bp)	64610513 - 64697567
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000153179 (version 83.38)
Entrez gene	283349
UniProt	Q86WH2 (UniProt - Evidence at protein level)
neXtProt	NX_Q86WH2
Antibodypedia	RASSF3 antibodies

PROTEIN BROWSER

RASSF3-001	RASSF3-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RASSF3-001 ENSP00000443021 ENST00000542104	Q86WH2 [Direct mapping] Ras association domain-containing protein 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005874 [microtubule] GO:0005886 [plasma membrane] GO:0007165 [signal transduction] GO:0042802 [identical protein binding] Show all	238 aa 27.6 kDa	No	0
RASSF3-201 ENSP00000336616 ENST00000336061	Q86WH2 [Direct mapping] Ras association domain-containing protein 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005874 [microtubule] GO:0005886 [plasma membrane] GO:0007165 [signal transduction] GO:0042802 [identical protein binding] Show all	238 aa 27.6 kDa	No	0