Tissue expression of NMRAL1 - Summary - The Human Protein Atlas

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NMRAL1

TISSUE

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CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	NMRAL1
Gene description	NmrA-like family domain containing 1
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	8
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Mixed
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Cytoplasmic expression in most tissues.

DATA RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA041353
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Mixed
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	NMRAL1 (HGNC Symbol)
Synonyms	FLJ25918, HSCARG, SDR48A1
Description	NmrA-like family domain containing 1 (HGNC Symbol)
Entrez gene summary	This gene encodes an NADPH sensor protein that preferentially binds to NADPH. The encoded protein also negatively regulates the activity of NF-kappaB in a ubiquitylation-dependent manner. It plays a key role in cellular antiviral response by negatively regulating the interferon response factor 3-mediated expression of interferon beta. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2015]
Chromosome	16
Cytoband	p13.3
Chromosome location (bp)	4461680 - 4495763
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000153406 (version 83.38)
Entrez gene	57407
UniProt	Q9HBL8 (UniProt - Evidence at protein level)
neXtProt	NX_Q9HBL8
Antibodypedia	NMRAL1 antibodies

PROTEIN BROWSER

NMRAL1-001	NMRAL1-002	NMRAL1-003	NMRAL1-004	NMRAL1-011	NMRAL1-014	NMRAL1-016	NMRAL1-018

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
NMRAL1-001 ENSP00000283429 ENST00000283429	Q9HBL8 [Direct mapping] NmrA-like family domain-containing protein 1 Show all	SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0048471 [perinuclear region of cytoplasm] Show all	299 aa 33.3 kDa	No	0
NMRAL1-002 ENSP00000458762 ENST00000574733	Q9HBL8 [Direct mapping] NmrA-like family domain-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0048471 [perinuclear region of cytoplasm] Show all	299 aa 33.3 kDa	No	0
NMRAL1-003 ENSP00000460263 ENST00000574425	Q9HBL8 [Direct mapping] NmrA-like family domain-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0048471 [perinuclear region of cytoplasm] Show all	299 aa 33.3 kDa	No	0
NMRAL1-004 ENSP00000383962 ENST00000404295	Q9HBL8 [Direct mapping] NmrA-like family domain-containing protein 1 Show all	SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0048471 [perinuclear region of cytoplasm] Show all	299 aa 33.3 kDa	No	0
NMRAL1-011 ENSP00000458425 ENST00000573571	I3L0Y6 [Direct mapping] NmrA-like family domain-containing protein 1 Show all	SCAMPI predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0005737 [cytoplasm] Show all	188 aa 20.8 kDa	No	0
NMRAL1-014 ENSP00000460476 ENST00000576176	I3L3I6 [Direct mapping] NmrA-like family domain-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		225 aa 24.4 kDa	No	0
NMRAL1-016 ENSP00000459221 ENST00000572232	I3L1Y8 [Direct mapping] NmrA-like family domain-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] Show all	190 aa 21.3 kDa	No	0
NMRAL1-018 ENSP00000460837 ENST00000572110	I3L3Z0 [Direct mapping] NmrA-like family domain-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] Show all	124 aa 14 kDa	No	0

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.