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CNKSR3

GENERAL INFORMATION

Gene name

 CNKSR3

Gene description

 CNKSR family member 3

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 4
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Mixed
GTEx:Mixed
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Ubiquitous nuclear expression.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data. Pending external verification. Caution, targets protein from more than one gene.

Reliability score

 Approved based on 2 antibodies.
HPA028708 , HPA049651
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 CNKSR3 (HGNC Symbol)

Synonyms

 FLJ31349, MAGI1

Description

 CNKSR family member 3 (HGNC Symbol)

Entrez gene summary

Chromosome

 6

Cytoband

 q25.2

Chromosome location (bp)

 154159828 - 154510659

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000153721 (version 83.38)

Entrez gene

 154043

UniProt

 Q6P9H4 (UniProt - Evidence at protein level)

neXtProt

 NX_Q6P9H4

Antibodypedia

 CNKSR3 antibodies

PROTEIN BROWSER
CNKSR3-001
CNKSR3-003
CNKSR3-005
CNKSR3-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
CNKSR3-001
ENSP00000475915
ENST00000607772
Q6P9H4 [Direct mapping]
Connector enhancer of kinase suppressor of ras 3
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0009966 [regulation of signal transduction]
GO:0010765 [positive regulation of sodium ion transport]
GO:0016020 [membrane]
GO:0033137 [negative regulation of peptidyl-serine phosphorylation]
GO:0070373 [negative regulation of ERK1 and ERK2 cascade]
GO:2000651 [positive regulation of sodium ion transmembrane transporter activity]
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 555 aa
61.9 kDa 		No 0
CNKSR3-003
ENSP00000393225
ENST00000424998
Q5T4Y8 [Direct mapping]
Connector enhancer of kinase suppressor of ras 3
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005737 [cytoplasm]
GO:0009966 [regulation of signal transduction]
GO:0016020 [membrane]
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 179 aa
19.6 kDa 		No 0
CNKSR3-005
ENSP00000418975
ENST00000479339
C9IZX4 [Direct mapping]
Connector enhancer of kinase suppressor of ras 3
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0009966 [regulation of signal transduction]
GO:0016020 [membrane]
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 475 aa
52.6 kDa 		No 0
CNKSR3-201
ENSP00000478800
ENST00000616478
G9CGD6 [Direct mapping]
CNK3/IPCEF1 fusion protein long isoform; Connector enhancer of kinase suppressor of ras 3
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0009966 [regulation of signal transduction]
GO:0016020 [membrane]
Show all
 899 aa
100.4 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.