We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.
Cancer tissues displayed weak to moderate cytoplasmic staining with additional nuclear positivity in few cases. Most of the cases of papillary carcinoma of thyroid along with few cases of lymphomas, endometrial, colorectal, breast and liver cancers were strongly positive. Majority of the cases of lymphomas, ovarian, cervical and skin cancers were negative.
GENE INFORMATION
Gene name
KCNJ16 (HGNC Symbol)
Synonyms
BIR9, Kir5.1
Description
Potassium channel, inwardly rectifying subfamily J, member 16 (HGNC Symbol)
Entrez gene summary
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which tends to allow potassium to flow into rather than out of a cell, can form heterodimers with two other inward-rectifier type potassium channels. It may function in fluid and pH balance regulation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Apr 2014]
