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PID1

GENERAL INFORMATION

Gene name

 PID1

Gene description

 Phosphotyrosine interaction domain containing 1

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 4
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression in several tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data.

Reliability score

 Approved based on 1 antibody.
HPA036103
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Heart muscle

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 PID1 (HGNC Symbol)

Synonyms

 FLJ20701, NYGGF4

Description

 Phosphotyrosine interaction domain containing 1 (HGNC Symbol)

Entrez gene summary

Chromosome

 2

Cytoband

 q36.3

Chromosome location (bp)

 228850526 - 229271285

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000153823 (version 83.38)

Entrez gene

 55022

UniProt

 Q7Z2X4 (UniProt - Evidence at protein level)

neXtProt

 NX_Q7Z2X4

Antibodypedia

 PID1 antibodies

PROTEIN BROWSER
PID1-001
PID1-002
PID1-004
PID1-005

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
PID1-001
ENSP00000375908
ENST00000392055
Q7Z2X4 [Direct mapping]
PTB-containing, cubilin and LRP1-interacting protein
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001933 [negative regulation of protein phosphorylation]
GO:0005515 [protein binding]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0006112 [energy reserve metabolic process]
GO:0010628 [positive regulation of gene expression]
GO:0010635 [regulation of mitochondrial fusion]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0046627 [negative regulation of insulin receptor signaling pathway]
GO:0051881 [regulation of mitochondrial membrane potential]
GO:0070346 [positive regulation of fat cell proliferation]
GO:0070584 [mitochondrion morphogenesis]
GO:0071345 [cellular response to cytokine stimulus]
GO:0071354 [cellular response to interleukin-6]
GO:0071356 [cellular response to tumor necrosis factor]
GO:0071398 [cellular response to fatty acid]
GO:0090005 [negative regulation of establishment of protein localization to plasma membrane]
GO:0090298 [negative regulation of mitochondrial DNA replication]
GO:2000045 [regulation of G1/S transition of mitotic cell cycle]
GO:2000377 [regulation of reactive oxygen species metabolic process]
GO:2000379 [positive regulation of reactive oxygen species metabolic process]
GO:2001170 [negative regulation of ATP biosynthetic process]
GO:2001171 [positive regulation of ATP biosynthetic process]
GO:2001274 [negative regulation of glucose import in response to insulin stimulus]
Show all
 217 aa
24.8 kDa 		No 0
PID1-002
ENSP00000386826
ENST00000409462
Q7Z2X4 [Direct mapping]
PTB-containing, cubilin and LRP1-interacting protein
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001933 [negative regulation of protein phosphorylation]
GO:0005515 [protein binding]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0006112 [energy reserve metabolic process]
GO:0010628 [positive regulation of gene expression]
GO:0010635 [regulation of mitochondrial fusion]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0046627 [negative regulation of insulin receptor signaling pathway]
GO:0051881 [regulation of mitochondrial membrane potential]
GO:0070346 [positive regulation of fat cell proliferation]
GO:0070584 [mitochondrion morphogenesis]
GO:0071345 [cellular response to cytokine stimulus]
GO:0071354 [cellular response to interleukin-6]
GO:0071356 [cellular response to tumor necrosis factor]
GO:0071398 [cellular response to fatty acid]
GO:0090005 [negative regulation of establishment of protein localization to plasma membrane]
GO:0090298 [negative regulation of mitochondrial DNA replication]
GO:2000045 [regulation of G1/S transition of mitotic cell cycle]
GO:2000377 [regulation of reactive oxygen species metabolic process]
GO:2000379 [positive regulation of reactive oxygen species metabolic process]
GO:2001170 [negative regulation of ATP biosynthetic process]
GO:2001171 [positive regulation of ATP biosynthetic process]
GO:2001274 [negative regulation of glucose import in response to insulin stimulus]
Show all
 168 aa
19.3 kDa 		No 0
PID1-004
ENSP00000375907
ENST00000392054
Q7Z2X4 [Direct mapping]
PTB-containing, cubilin and LRP1-interacting protein
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001933 [negative regulation of protein phosphorylation]
GO:0005515 [protein binding]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0006112 [energy reserve metabolic process]
GO:0010628 [positive regulation of gene expression]
GO:0010635 [regulation of mitochondrial fusion]
GO:0044320 [cellular response to leptin stimulus]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0046325 [negative regulation of glucose import]
GO:0046627 [negative regulation of insulin receptor signaling pathway]
GO:0051881 [regulation of mitochondrial membrane potential]
GO:0070346 [positive regulation of fat cell proliferation]
GO:0070584 [mitochondrion morphogenesis]
GO:0071345 [cellular response to cytokine stimulus]
GO:0071354 [cellular response to interleukin-6]
GO:0071356 [cellular response to tumor necrosis factor]
GO:0071398 [cellular response to fatty acid]
GO:0090005 [negative regulation of establishment of protein localization to plasma membrane]
GO:0090298 [negative regulation of mitochondrial DNA replication]
GO:2000045 [regulation of G1/S transition of mitotic cell cycle]
GO:2000377 [regulation of reactive oxygen species metabolic process]
GO:2000379 [positive regulation of reactive oxygen species metabolic process]
GO:2001170 [negative regulation of ATP biosynthetic process]
GO:2001171 [positive regulation of ATP biosynthetic process]
GO:2001274 [negative regulation of glucose import in response to insulin stimulus]
Show all
 248 aa
28.1 kDa 		No 0
PID1-005
ENSP00000283937
ENST00000354069
Q7Z2X4 [Direct mapping]
PTB-containing, cubilin and LRP1-interacting protein
Show all
   SPOCTOPUS predicted secreted proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001933 [negative regulation of protein phosphorylation]
GO:0005515 [protein binding]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0006112 [energy reserve metabolic process]
GO:0010628 [positive regulation of gene expression]
GO:0010635 [regulation of mitochondrial fusion]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0046627 [negative regulation of insulin receptor signaling pathway]
GO:0051881 [regulation of mitochondrial membrane potential]
GO:0070346 [positive regulation of fat cell proliferation]
GO:0070584 [mitochondrion morphogenesis]
GO:0071345 [cellular response to cytokine stimulus]
GO:0071354 [cellular response to interleukin-6]
GO:0071356 [cellular response to tumor necrosis factor]
GO:0071398 [cellular response to fatty acid]
GO:0090005 [negative regulation of establishment of protein localization to plasma membrane]
GO:0090298 [negative regulation of mitochondrial DNA replication]
GO:2000045 [regulation of G1/S transition of mitotic cell cycle]
GO:2000377 [regulation of reactive oxygen species metabolic process]
GO:2000379 [positive regulation of reactive oxygen species metabolic process]
GO:2001170 [negative regulation of ATP biosynthetic process]
GO:2001171 [positive regulation of ATP biosynthetic process]
GO:2001274 [negative regulation of glucose import in response to insulin stimulus]
Show all
 250 aa
28.3 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.