Expression of NUS1 in cancer - Summary - The Human Protein Atlas

CANCER ATLAS

Gene description

NUS1 dehydrodolichyl diphosphate synthase subunit

Protein class

Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Melanoma

STAINING SUMMARY

HPA027504

GENE INFORMATION
Gene name	NUS1 (HGNC Symbol)
Synonyms	C6orf68, MGC7199, NgBR, TANGO14
Description	NUS1 dehydrodolichyl diphosphate synthase subunit (HGNC Symbol)
Entrez gene summary
Chromosome	6
Cytoband	q22.1
Chromosome location (bp)	117675502 - 117710640
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000153989 (version 83.38)
Entrez gene	116150
UniProt	Q96E22 (UniProt - Evidence at protein level)
neXtProt	NX_Q96E22
Antibodypedia	NUS1 antibodies

PROTEIN BROWSER

NUS1-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
NUS1-001 ENSP00000357480 ENST00000368494	Q96E22 [Direct mapping] Dehydrodolichyl diphosphate syntase complex subunit NUS1 Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Disease related genes Potential drug targets Protein evidence (Ezkurdia et al 2014) Show all	GO:0001525 [angiogenesis] GO:0003674 [molecular_function] GO:0004659 [prenyltransferase activity] GO:0005515 [protein binding] GO:0005789 [endoplasmic reticulum membrane] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0016765 [transferase activity, transferring alkyl or aryl (other than methyl) groups] GO:0019408 [dolichol biosynthetic process] GO:0030154 [cell differentiation] GO:0032383 [regulation of intracellular cholesterol transport] GO:0035268 [protein mannosylation] GO:0042632 [cholesterol homeostasis] GO:0055092 [sterol homeostasis] Show all	293 aa 33.2 kDa	No	1