Expression of SEMA3D in cancer - Summary

CANCER ATLAS

Gene description

Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA037522

GENE INFORMATION
Gene name	SEMA3D (HGNC Symbol)
Synonyms	coll-2, Sema-Z2
Description	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D (HGNC Symbol)
Entrez gene summary
Chromosome	7
Cytoband	q21.11
Chromosome location (bp)	84995553 - 85186855
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000153993 (version 83.38)
Entrez gene	223117
UniProt	O95025 (UniProt - Evidence at transcript level)
neXtProt	NX_O95025
Antibodypedia	SEMA3D antibodies

PROTEIN BROWSER

SEMA3D-001	SEMA3D-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SEMA3D-001 ENSP00000284136 ENST00000284136	O95025 [Direct mapping] Semaphorin-3D Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Show all	GO:0001755 [neural crest cell migration] GO:0005515 [protein binding] GO:0005615 [extracellular space] GO:0030215 [semaphorin receptor binding] GO:0030335 [positive regulation of cell migration] GO:0038191 [neuropilin binding] GO:0045499 [chemorepellent activity] GO:0048843 [negative regulation of axon extension involved in axon guidance] GO:0050919 [negative chemotaxis] GO:0071526 [semaphorin-plexin signaling pathway] Show all	777 aa 89.7 kDa	No	0
SEMA3D-002 ENSP00000401366 ENST00000444867	C9JYT6 [Direct mapping] Semaphorin-3D Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0016021 [integral component of membrane] Show all	294 aa 33.6 kDa	No	0