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TOMM70A

GENERAL INFORMATION

Gene name

 TOMM70A

Gene description

 Translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)

Protein class

 Predicted membrane proteins

Predicted localization

 Membrane

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 General cytoplasmic expression with a granular pattern.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data.

Reliability score

 Supported based on 3 antibodies.
HPA014589 , HPA048020 , CAB017156
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 TOMM70A (HGNC Symbol)

Synonyms

 KIAA0719

Description

 Translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae) (HGNC Symbol)

Entrez gene summary

 This gene encodes an import receptor of the outer mitochondrial membrane that is part of the translocase of the outer membrane complex. This protein is involved in the import of mitochondrial precursor proteins. [provided by RefSeq, Oct 2011]

Chromosome

 3

Cytoband

 q12.2

Chromosome location (bp)

 100363431 - 100401398

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000154174 (version 83.38)

Entrez gene

 9868

UniProt

 O94826 (UniProt - Evidence at protein level)

neXtProt

 NX_O94826

Antibodypedia

 TOMM70A antibodies

PROTEIN BROWSER
TOMM70A-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
TOMM70A-001
ENSP00000284320
ENST00000284320
O94826 [Direct mapping]
Mitochondrial import receptor subunit TOM70
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Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0000423 [macromitophagy]
GO:0005515 [protein binding]
GO:0005739 [mitochondrion]
GO:0005741 [mitochondrial outer membrane]
GO:0005742 [mitochondrial outer membrane translocase complex]
GO:0006626 [protein targeting to mitochondrion]
GO:0008320 [protein transmembrane transporter activity]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0016236 [macroautophagy]
GO:0044267 [cellular protein metabolic process]
GO:0070062 [extracellular exosome]
GO:0071806 [protein transmembrane transport]
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 608 aa
67.5 kDa 		No 1

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.