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ABCA10

GENERAL INFORMATION

Gene name

 ABCA10

Gene description

 ATP-binding cassette, sub-family A (ABC1), member 10

Protein class

 Predicted intracellular proteins
Predicted membrane proteins
Transporters

Predicted localization

 Intracellular,Membrane

Number of transcripts

 3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Mixed
GTEx:Tissue enhanced (ovary)
FANTOM5:Mixed

Protein evidence

 Evidence at protein level

Protein expression

 General cytoplasmic expression.

DATA RELIABILITY

Data reliability
description

 Antibody staining not consistent with RNA expression data. Pending external verification.

Reliability score

 Uncertain based on 1 antibody.
HPA014535
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (ovary)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed

GENE INFORMATION

Gene name

 ABCA10 (HGNC Symbol)

Synonyms

 EST698739

Description

 ATP-binding cassette, sub-family A (ABC1), member 10 (HGNC Symbol)

Entrez gene summary

 The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This encoded protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This gene is clustered among 4 other ABC1 family members on 17q24, but neither the substrate nor the function of this gene is known. [provided by RefSeq, Jul 2008]

Chromosome

 17

Cytoband

 q24.3

Chromosome location (bp)

 69147214 - 69244846

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000154263 (version 83.38)

Entrez gene

 10349

UniProt

 Q8WWZ4 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q8WWZ4

Antibodypedia

 ABCA10 antibodies

PROTEIN BROWSER
ABCA10-001
ABCA10-010
ABCA10-011

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
ABCA10-001
ENSP00000269081
ENST00000269081
Q8WWZ4 [Direct mapping]
ATP-binding cassette sub-family A member 10
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Transporters
   Primary Active Transporters
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   >9TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Show all
GO:0005524 [ATP binding]
GO:0006869 [lipid transport]
GO:0008152 [metabolic process]
GO:0016021 [integral component of membrane]
GO:0016887 [ATPase activity]
GO:0042626 [ATPase activity, coupled to transmembrane movement of substances]
GO:0043231 [intracellular membrane-bounded organelle]
GO:0055085 [transmembrane transport]
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 1543 aa
175.8 kDa 		No >9
ABCA10-010
ENSP00000466506
ENST00000521538
K7EMH5 [Direct mapping]
ATP-binding cassette sub-family A member 10
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Predicted intracellular proteins
Show all
GO:0006869 [lipid transport]
GO:0016021 [integral component of membrane]
GO:0042626 [ATPase activity, coupled to transmembrane movement of substances]
GO:0043231 [intracellular membrane-bounded organelle]
GO:0055085 [transmembrane transport]
Show all
 76 aa
8.4 kDa 		No 0
ABCA10-011
ENSP00000468351
ENST00000522787
K7ERP5 [Direct mapping]
ATP-binding cassette sub-family A member 10
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Predicted intracellular proteins
Show all
GO:0006869 [lipid transport]
GO:0016021 [integral component of membrane]
GO:0042626 [ATPase activity, coupled to transmembrane movement of substances]
GO:0043231 [intracellular membrane-bounded organelle]
GO:0055085 [transmembrane transport]
Show all
 45 aa
5.3 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.