Expression of BTG3 in cancer - Summary - The Human Protein Atlas

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BTG3

TISSUE

CELL

CANCER

CANCER ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

CANCER ATLAS

Gene description

BTG family, member 3

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA018400

GENE INFORMATION
Gene name	BTG3 (HGNC Symbol)
Synonyms	ANA, tob55
Description	BTG family, member 3 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is a member of the BTG/Tob family. This family has structurally related proteins that appear to have antiproliferative properties. This encoded protein might play a role in neurogenesis in the central nervous system. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
Chromosome	21
Cytoband	q21.1
Chromosome location (bp)	17593653 - 17612947
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000154640 (version 83.38)
Entrez gene	10950
UniProt	Q14201 (UniProt - Evidence at protein level)
neXtProt	NX_Q14201
Antibodypedia	BTG3 antibodies

PROTEIN BROWSER

BTG3-001	BTG3-002	BTG3-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
BTG3-001 ENSP00000344609 ENST00000339775	Q14201 [Direct mapping] Protein BTG3 Show all	MEMSAT-SVM predicted membrane proteins SCAMPI predicted membrane proteins Phobius predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0008285 [negative regulation of cell proliferation] GO:0045930 [negative regulation of mitotic cell cycle] Show all	296 aa 34.2 kDa	No	0
BTG3-002 ENSP00000284879 ENST00000348354	Q14201 [Direct mapping] Protein BTG3 Q6IAU3 [Target identity:100%; Query identity:100%] BTG family, member 3, isoform CRA_b; BTG3 protein; cDNA FLJ75072, highly similar to Homo sapiens BTG family, member 3 (BTG3), mRNA Show all	Phobius predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0008285 [negative regulation of cell proliferation] GO:0045930 [negative regulation of mitotic cell cycle] Show all	252 aa 29.1 kDa	No	0
BTG3-003 ENSP00000413799 ENST00000457956	C9JLA2 [Direct mapping] Protein BTG3 Show all	Phobius predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		46 aa 5.6 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.