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Malignant tissues were generally negative. Several cases of prostate cancer displayed moderate to strong cytoplasmic staining.
GENE INFORMATION
Gene name
WNT7A
Synonyms
Description
Wingless-type MMTV integration site family, member 7A (HGNC Symbol)
Entrez gene summary
This gene is a member of the WNT gene family, which consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is involved in the development of the anterior-posterior axis in the female reproductive tract, and also plays a critical role in uterine smooth muscle pattering and maintenance of adult uterine function. Mutations in this gene are associated with Fuhrmann and Al-Awadi/Raas-Rothschild/Schinzel phocomelia syndromes. [provided by RefSeq, Jul 2008]