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PLCL2

CANCER ATLAS

Gene description

 Phospholipase C-like 2

Protein class

 Predicted intracellular proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA047616

GENE INFORMATION

Gene name

 PLCL2 (HGNC Symbol)

Synonyms

 KIAA1092, PLCE2

Description

 Phospholipase C-like 2 (HGNC Symbol)

Entrez gene summary

Chromosome

 3

Cytoband

 p24.3

Chromosome location (bp)

 16802651 - 17090594

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000154822 (version 83.38)

Entrez gene

 23228

UniProt

 Q9UPR0 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9UPR0

Antibodypedia

 PLCL2 antibodies

PROTEIN BROWSER
PLCL2-002
PLCL2-003
PLCL2-004

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
PLCL2-002
ENSP00000478458
ENST00000615277
Q9UPR0 [Direct mapping]
Inactive phospholipase C-like protein 2
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0002322 [B cell proliferation involved in immune response]
GO:0002337 [B-1a B cell differentiation]
GO:0004435 [phosphatidylinositol phospholipase C activity]
GO:0004871 [signal transducer activity]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0006629 [lipid metabolic process]
GO:0007165 [signal transduction]
GO:0007214 [gamma-aminobutyric acid signaling pathway]
GO:0008081 [phosphoric diester hydrolase activity]
GO:0032228 [regulation of synaptic transmission, GABAergic]
GO:0033135 [regulation of peptidyl-serine phosphorylation]
GO:0035556 [intracellular signal transduction]
GO:0050811 [GABA receptor binding]
GO:0050859 [negative regulation of B cell receptor signaling pathway]
GO:1900122 [positive regulation of receptor binding]
Show all
 1127 aa
125.9 kDa 		No 0
PLCL2-003
ENSP00000412836
ENST00000432376
Q9UPR0 [Direct mapping]
Inactive phospholipase C-like protein 2
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004435 [phosphatidylinositol phospholipase C activity]
GO:0004871 [signal transducer activity]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0006629 [lipid metabolic process]
GO:0007165 [signal transduction]
GO:0008081 [phosphoric diester hydrolase activity]
GO:0035556 [intracellular signal transduction]
GO:0050811 [GABA receptor binding]
Show all
 1001 aa
113.6 kDa 		No 0
PLCL2-004
ENSP00000404433
ENST00000419842
H7C276 [Direct mapping]
Phosphoinositide phospholipase C
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004435 [phosphatidylinositol phospholipase C activity]
GO:0004871 [signal transducer activity]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0006629 [lipid metabolic process]
GO:0007165 [signal transduction]
GO:0008081 [phosphoric diester hydrolase activity]
GO:0016042 [lipid catabolic process]
GO:0035556 [intracellular signal transduction]
Show all
 704 aa
79.8 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.