Expression of SKA1 in cancer - Summary - The Human Protein Atlas

CANCER ATLAS

Gene description

Spindle and kinetochore associated complex subunit 1

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA045495

GENE INFORMATION
Gene name	SKA1 (HGNC Symbol)
Synonyms	C18orf24, MGC10200
Description	Spindle and kinetochore associated complex subunit 1 (HGNC Symbol)
Entrez gene summary
Chromosome	18
Cytoband	q21.1
Chromosome location (bp)	50374995 - 50394173
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000154839 (version 83.38)
Entrez gene	220134
UniProt	Q96BD8 (UniProt - Evidence at protein level)
neXtProt	NX_Q96BD8
Antibodypedia	SKA1 antibodies

PROTEIN BROWSER

SKA1-001	SKA1-002	SKA1-003	SKA1-004	SKA1-005

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SKA1-001 ENSP00000285116 ENST00000285116	Q96BD8 [Direct mapping] Spindle and kinetochore-associated protein 1 A0A024R294 [Target identity:100%; Query identity:100%] Chromosome 18 open reading frame 24, isoform CRA_a Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000278 [mitotic cell cycle] GO:0000940 [condensed chromosome outer kinetochore] GO:0005515 [protein binding] GO:0005829 [cytosol] GO:0005876 [spindle microtubule] GO:0007059 [chromosome segregation] GO:0007067 [mitotic nuclear division] GO:0007264 [small GTPase mediated signal transduction] GO:0008017 [microtubule binding] GO:0015630 [microtubule cytoskeleton] GO:0031110 [regulation of microtubule polymerization or depolymerization] GO:0051301 [cell division] Show all	255 aa 29.5 kDa	No	0
SKA1-002 ENSP00000467559 ENST00000494518	K7EPW0 [Direct mapping] Spindle and kinetochore-associated protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		91 aa 10.8 kDa	No	0
SKA1-003 ENSP00000467242 ENST00000488454	K7EP61 [Direct mapping] Spindle and kinetochore-associated protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		104 aa 12.3 kDa	No	0
SKA1-004 ENSP00000397222 ENST00000417656	Q96BD8 [Direct mapping] Spindle and kinetochore-associated protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000278 [mitotic cell cycle] GO:0000940 [condensed chromosome outer kinetochore] GO:0005515 [protein binding] GO:0005829 [cytosol] GO:0005876 [spindle microtubule] GO:0007059 [chromosome segregation] GO:0007067 [mitotic nuclear division] GO:0007264 [small GTPase mediated signal transduction] GO:0008017 [microtubule binding] GO:0015630 [microtubule cytoskeleton] GO:0031110 [regulation of microtubule polymerization or depolymerization] GO:0051301 [cell division] Show all	209 aa 24.4 kDa	No	0
SKA1-005 ENSP00000381470 ENST00000398452	Q96BD8 [Direct mapping] Spindle and kinetochore-associated protein 1 A0A024R294 [Target identity:100%; Query identity:100%] Chromosome 18 open reading frame 24, isoform CRA_a Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000278 [mitotic cell cycle] GO:0000940 [condensed chromosome outer kinetochore] GO:0005515 [protein binding] GO:0005829 [cytosol] GO:0005876 [spindle microtubule] GO:0007059 [chromosome segregation] GO:0007067 [mitotic nuclear division] GO:0007264 [small GTPase mediated signal transduction] GO:0008017 [microtubule binding] GO:0015630 [microtubule cytoskeleton] GO:0031110 [regulation of microtubule polymerization or depolymerization] GO:0051301 [cell division] Show all	255 aa 29.5 kDa	No	0