Cell atlas - TRMT44 - The Human Protein Atlas

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TRMT44

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nucleoplasm

Human cell
	Nucleoplasm

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GENERAL INFORMATION
Gene name	TRMT44
Gene description	TRNA methyltransferase 44 homolog (S. cerevisiae)
Protein class	Enzymes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the nucleoplasm.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoplasm (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA045461
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the nucleoplasm.

Main location

Nucleoplasm (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA045461	PC-3	Nucleoplasm
	HPA045461	U-2 OS	No staining
	HPA045461	U-251 MG	No staining

GENE INFORMATION
Gene name	TRMT44 (HGNC Symbol)
Synonyms	C4orf23, FLJ35725, METTL19, TRM44
Description	TRNA methyltransferase 44 homolog (S. cerevisiae) (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is a putative tRNA methyltransferase found in the cytoplasm. Defects in this gene may be a cause of partial epilepsy with pericentral spikes (PEPS), but that has not been proven definitively. [provided by RefSeq, May 2012]
Chromosome	4
Cytoband	p16.1
Chromosome location (bp)	8436140 - 8493531
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000155275 (version 83.38)
Entrez gene	152992
UniProt	Q8IYL2 (UniProt - Evidence at transcript level)
neXtProt	NX_Q8IYL2
Antibodypedia	TRMT44 antibodies

PROTEIN BROWSER

TRMT44-001	TRMT44-002	TRMT44-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TRMT44-001 ENSP00000374387 ENST00000389737	Q8IYL2 [Direct mapping] Probable tRNA (uracil-O(2)-)-methyltransferase Show all	Enzymes ENZYME proteins Transferases Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005737 [cytoplasm] GO:0006400 [tRNA modification] GO:0008033 [tRNA processing] GO:0008168 [methyltransferase activity] GO:0010467 [gene expression] GO:0016300 [tRNA (uracil) methyltransferase activity] GO:0030488 [tRNA methylation] GO:0046872 [metal ion binding] Show all	757 aa 84.6 kDa	No	0
TRMT44-002 ENSP00000424643 ENST00000513449	Q8IYL2 [Direct mapping] Probable tRNA (uracil-O(2)-)-methyltransferase Show all	Enzymes ENZYME proteins Transferases Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005737 [cytoplasm] GO:0006400 [tRNA modification] GO:0008033 [tRNA processing] GO:0008168 [methyltransferase activity] GO:0010467 [gene expression] GO:0016300 [tRNA (uracil) methyltransferase activity] GO:0030488 [tRNA methylation] GO:0046872 [metal ion binding] Show all	411 aa 46.6 kDa	No	0
TRMT44-003 ENSP00000434207 ENST00000504134	H0YDS2 [Direct mapping] Probable tRNA (uracil-O(2)-)-methyltransferase Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		220 aa 23.5 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.