Cell atlas - MIER3 - The Human Protein Atlas

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MIER3

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nucleoplasm

Human cell
	Nucleoplasm

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GENERAL INFORMATION
Gene name	MIER3
Gene description	Mesoderm induction early response 1, family member 3
Protein class	Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	6
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the nucleoplasm.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoplasm (validated)

DATA RELIABILITY
Reliability score	Validated based on 2 antibodies. HPA058349 , HPA065946
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ASSAYS

RNA expression

Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the nucleoplasm.

Main location

Nucleoplasm (validated)


	Toggle channels	Low High G1 S G2 M N/A

Antibody	Cell line	Location
HPA058349	A549	Nucleoplasm
HPA058349	U-2 OS	Nucleoplasm
HPA058349	U-251 MG	Nucleoplasm
HPA065946	CACO-2	Nucleoplasm
HPA065946	SH-SY5Y	Nucleoplasm
HPA065946	U-2 OS	Nucleoplasm

GENE INFORMATION
Gene name	MIER3 (HGNC Symbol)
Synonyms	DKFZp686L09111, DKFZp781I1119, FLJ35954
Description	Mesoderm induction early response 1, family member 3 (HGNC Symbol)
Entrez gene summary
Chromosome	5
Cytoband	q11.2
Chromosome location (bp)	56919602 - 56971675
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000155545 (version 83.38)
Entrez gene	166968
UniProt	Q7Z3K6 (UniProt - Evidence at protein level)
neXtProt	NX_Q7Z3K6
Antibodypedia	MIER3 antibodies

PROTEIN BROWSER

MIER3-001	MIER3-003	MIER3-004	MIER3-005	MIER3-008	MIER3-011

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
MIER3-001 ENSP00000370611 ENST00000381213	Q7Z3K6 [Direct mapping] Mesoderm induction early response protein 3 Show all	Predicted intracellular proteins Transcription factors Helix-turn-helix domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003677 [DNA binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] Show all	549 aa 61.3 kDa	No	0
MIER3-003 ENSP00000370624 ENST00000381226	Q7Z3K6 [Direct mapping] Mesoderm induction early response protein 3 Show all	Predicted intracellular proteins Transcription factors Helix-turn-helix domains Protein evidence (Ezkurdia et al 2014) Show all	GO:0003677 [DNA binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] Show all	555 aa 62 kDa	No	0
MIER3-004 ENSP00000370596 ENST00000381199	Q7Z3K6 [Direct mapping] Mesoderm induction early response protein 3 Show all	Predicted intracellular proteins Transcription factors Helix-turn-helix domains Protein evidence (Ezkurdia et al 2014) Show all	GO:0003677 [DNA binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] Show all	550 aa 61.4 kDa	No	0
MIER3-005 ENSP00000386584 ENST00000409421	Q7Z3K6 [Direct mapping] Mesoderm induction early response protein 3 Show all	Predicted intracellular proteins Transcription factors Helix-turn-helix domains Protein evidence (Ezkurdia et al 2014) Show all	GO:0003677 [DNA binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] Show all	487 aa 54.4 kDa	No	0
MIER3-008 ENSP00000337027 ENST00000336942	A8MQD4 [Direct mapping] Mesoderm induction early response protein 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		145 aa 16 kDa	No	0
MIER3-011 ENSP00000407169 ENST00000440000	C9JXP7 [Direct mapping] Mesoderm induction early response protein 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		24 aa 2.7 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.